Agent Name
1-Chloro-1-nitropropane
Major Category
Pesticides
Synonyms
Chloronitropropane; Propane, 1-chloro-1-nitro-; [ChemIDplus] Korax; [ACGIH]
Description
Colorless liquid with an unpleasant odor. [fungicide]; [NIOSH]
Sources/Uses
Has been used as a rubber cement additive; formerly used in the USA as a fungicide; [ACGIH]
Comments
1-Chloro-1-nitropropane causes pulmonary edema, liver injury, and death in animals exposed to high concentrations. "A 6-hour inhalation exposure of 393 ppm killed one of two rabbits, but neither of two exposed guinea pigs died." TLV Basis is eye irritation, upper respiratory tract irritation and pulmonary edema; [ACGIH] A lachrymator; [HSDB]
Skin Designation (ACGIH)
Insufficient data
Lethal Concentration
LCLo (rabbits) = 2,000 mg/m3/6h
Explanatory Notes
VP from HSDB;
NFPA
high ambient temp required
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Processes
Industrial Processes with risk of exposure: