Bensulide

Synonyms

Benzenesulfonamide, N-(2-mercaptoethyl)-, S-ester with O,O-diisopropylphosphorodithioate; Benzulfide; Betamec; Betasan; Betasan E; Betasan G; Betasan [OBSOLETE]; Disan; Disan (pesticide); Exporsan; Kayaphenone; N-(2-(O,O-Diisopropyldithiophosphoryl)ethyl)benzenesulfonamide; N-(2-Ethylthio)benzene sulphonamide-S,O,O-diisopropylphosphorodithioate; N-(2-Mercaptoethyl)benzenesulfonamide S-(O,O-diisopropyl phosphorodithioate); N-(2-Mercaptoethylbenzene)sulfonamide S-(O,O-diisopropylphosphorodithioate); N-(beta-O,O-Diisopropyldithiophosphorylethyl)benzenesulfonamide; O,O-Bis(1-methylethyl) S-(2-((phenylsulfonyl)amino)ethyl)phosphorodithioate (9CI); O,O-Bis(1-methylethyl)-S-(2-((phenylsulfonyl)amino)ethyl) phosphorodithioate; O,O-Di-isopropyl S-2-phenylsulphonylaminoethyl phosphorodithioate; O,O-Diisopropyl 2-(benzenesulfonamido)ethyl dithiophosphate; O,O-Diisopropyl S-(2-benzenesulfonylaminoethyl) phosphorodithioate; O,O-Diisopropyl dithiophosphate S-ester with N-(2-mercaptoethyl)benzenesulphonamide; O,O-Diisopropyl phosphorodithioate S-ester with N-(2-mercaptoethyl)benzenesulfonamide; Phosphorodithioic acid, O,O-bis(1-methylethyl) S-(2-((phenylsulfonyl)amino)ethyl) ester; Phosphorodithioic acid, O,O-diisopropyl ester, S-ester with N-(2-mercaptoethyl)benzenesulfonamide; Pre-San; Prefar; Prefar E; Prefer; R 4461; R-4461; S-(O,O-Diisopropyl phosphorodithioate) ester of N-(2-mercaptoethyl)benzenesulfonamide; S-(O,O-Diisopropylphosphorodithioate) of N-(2-mercaptoethyl)benzenesulfonamide; S-2-Benzenesulfonamidoethyl O,O-di-isopropyl phosphorodithioate; S-2-Benzenesulphonamidoethyl O,O-diisopropyl phosphorodithioate; S-beta-(Benzenesulfonamido)ethyl O,O-diisopropyl dithiophosphate; SAP; SAP (herbicide); [ChemIDplus]

Category

Organophosphate Insecticides

Description

Colorless to white solid; mp = 34 deg C; [ICSC] Colorless or amber liquid above 34.4 deg C; [HSDB] Amber liquid; mp = 33-36 deg C; Supercools and may remain liquid below these temperatures; [MSDSonline]

Sources/Uses

Used as a pre-emergence herbicide for control of annual grasses and broad-leaved weeds in lawns, turf, watermelons, cotton, rice, vegetables, rice, and other crops; [HSDB]

Comments

A cholinesterase inhibitor; [ICSC] Caused mild skin and eye irritation in rabbits; Effects observed in chronic feeding studies with rats include inhibition of cholinesterase activity and minor histopathological changes of liver; [HSDB] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]

Reference Link #1

Biomedical References

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

0.1 mg/m3, Inhalable fraction and vapor

8E-07 mm Hg

LC50 (rat) > 1,750 mg/m3/4h

Explanatory Notes

Flash point = 157 deg C; [HSDB]

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Not Classifiable

Other Poison

Organophosphate

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)