Hexachlorobutadiene
Agent Name
Hexachlorobutadiene
CAS Number
87-68-3
Formula
C4-Cl6
Major Category
Other Classes
Synonyms
1,1,2,3,4,4-Hexachloro-1,3-butadiene; 1,3-Butadiene, 1,1,2,3,4,4-hexachloro-; 1,3-Butadiene, hexachloro-; 1,3-Hexachlorobutadiene; C 46; C-46; Dolen-pur; GP-40-66:120; HCBD; Hexachlor-1,3-butadien [Czech]; Hexachlorobutadiene; Perchlorobutadiene; [ChemIDplus] UN2279
Category
Halogenated Aliphatics, Unsaturated
Description
Clear, colorless liquid with a mild, turpentine-like odor; [NIOSH]
Sources/Uses
Used as a solvent, heat transfer liquid in transformers, and hydraulic fluid; produced as a byproduct of hydrocarbon chlorination processes; [ACGIH] Used as a fumigant in parts of Europe against Phylloxera on grapes; [HSDB]
Comments
Kidney injury reported in chronic feeding and inhalation studies of experimental animals; [ACGIH] Liquid is corrosive. Vapor causes skin, eye, and respiratory tract irritation. May cause kidney injury; [ICSC] Irritating to skin; Toxic by ingestion, inhalation, or skin absorption; [MSDSonline]
Biomedical References
Exposure Assessment
Skin Designation (ACGIH)
Yes
TLV (ACGIH)
0.02 ppm
MAK
0.02 ppm
Vapor Pressure
0.2 mm Hg
Odor Threshold Low
1.1 ppm
Lethal Concentration
LC50 (mouse) = 370 mg/m3
Explanatory Notes
Flash point = 90 deg C; Odor threshold from CHEMINFO; VP from HSDB;
Reference Link #2
NFPA
must be preheated
ERPG-1
1 ppm
ERPG-2
3 ppm
ERPG-3
10 ppm
Adverse Effects
Nephrotoxin
Yes
Dermatotoxin
Skin burns
IARC Carcinogen
Not classifiable
ACGIH Carcinogen
Confirmed Animal
Diseases, Processes, and Activities Linked to This Agent
Processes
Industrial Processes with risk of exposure: