Propyleneimine

Synonyms

1,2-Propyleneimine; 1,2-Propylenimine; 2-Methylazacyclopropane; 2-Methylaziridine; 2-Methylethylenimine; Aziridine, 2-methyl-; Methylaziridine; Methylethylenimine; Propilenimina [Spanish]; Propylene imine; Propyleneimine; Propylenimine; [ChemIDplus] UN1921

Category

Other Nitrogen Compounds

Description

Colorless, oily liquid with an ammonia-like odor; [NIOSH]

Sources/Uses

Used as an intermediate in the rubber and pharmaceutical industries; Used as a modifier and monomer in advanced composites; [HSDB]

Comments

At higher concentrations, may cause blistering and necrosis of the skin; Toxicity is similar to that of ethyleneimine; Causes severe injuries to the kidneys (tubular necrosis) in acute animal experiments and tumors in chronic ones; [HSDB] An irritant of the skin, eyes, and respiratory tract; [ICSC] Suspected germ cell mutagen (3B); [MAK] Propyleneimine, stabilized (UN1921) has warning of explosive polymerization; [ERG 2016]

Biomedical References

Yes

0.2 ppm

0.4 ppm

2 ppm

100 ppm

Excerpts from Documentation for IDLHs

It has been reported that rats survived a 2­hour exposure to 500 ppm and guinea pigs survived a 30­minute exposure to 500 ppm [Carpenter et al. 1948].

140 mm Hg

LCLo (rat) = 500 ppm/4 hr

Yes

Explanatory Notes

Flash point = -3 deg C; VP from HSDB;

Yes

Yes

Skin burns

Possible (2b)

Anticipated human carcinogen

Confirmed Animal

Processes

Industrial Processes with risk of exposure:

• Plastic Composites Manufacturing