o-Tolidine

Agent Name
o-Tolidine
Alternative Name
3,3'-Dimethylbenzidine
CAS Number
119-93-7
Formula
C14-H16-N2
Major Category
Nitrogen Compounds
o-Tolidine formula graphical representation
Synonyms
3,3'-Dimethylbenzidine; 2-Tolidin [German]; 2-Tolidina [Italian]; 2-Tolidine; 3,3'-Dimethyl-(1,1'-biphenyl)-4,4'-diamine; 3,3'-Dimethyl-4,4'-biphenyldiamine; 3,3'-Dimethyl-4,4'-diaminobiphenyl; 3,3'-Dimethyl-4,4'-diphenyldiamine; 3,3'-Dimethylbenzidine; 3,3'-Tolidine; 4,4'-Bi-o-toluidine; 4,4'-Di-o-toluidine; 4,4'-Diamino-3,3'-dimethylbiphenyl; 4,4'-Diamino-3,3'-dimethyldiphenyl; Bianisidine; C.I. 37230; C.I. Azoic Diazo Component 113; CI 37230; CI Azoic diazo component 113; Diaminoditolyl; Diaminotolyl; Fast Dark Blue Base R; Orthotolidine; o-Tolidine; [ChemIDplus]
Category
Benzidine and Derivatives
Description
White to reddish crystals or powder. [Note: Darkens on exposure to air. Often used in paste or wet cake form. Used as a basis for many dyes.]; [NIOSH]
Sources/Uses
Used as an intermediate in the production of dyes and pigments; used as a curing agent for polyurethane elastomers, coatings, and rigid foams; [HSDB]
Comments
A carcinogen in experimental animals; [HSDB] In subchronic feeding studies, animals develop liver and kidney damage and bone marrow depression. [ACGIH] See "Benzidine."
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Yes
Vapor Pressure
1E-06 mm Hg
Explanatory Notes
Carcinogen--No TLV; NIOSH recommends 60 minute ceiling of 0.02 mg/m3; Flash point = 137 deg C; VP from HSDB;

Adverse Effects

Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Possible (2b)
NTP Carcinogen
Anticipated human carcinogen
ACGIH Carcinogen
Confirmed Animal

Diseases, Processes, and Activities Linked to This Agent

Processes

Industrial Processes with risk of exposure: