o-Dichlorobenzene

Agent Name
o-Dichlorobenzene
Alternative Name
1,2-Dichlorobenzene
CAS Number
95-50-1
Formula
C6-H4-Cl2
Major Category
Solvents
o-Dichlorobenzene formula graphical representation
Synonyms
1,2-Dichlorobenzene; Chloroben; Cloroben; DCB; Dichlorobenzene, ortho, liquid; Dilantin DB; Dilatin DB; Dizene; Dowtherm E; Orthodichlorobenzene; Orthodichlorobenzol; Special termite fluid; Termitkil; o-Dichlor benzol; o-Dichlorbenzol; o-Dichlorobenzene; o-Dichlorobenzol; [ChemIDplus] UN1591
Category
Chlorinated Aromatics
Description
Colorless to pale-yellow liquid with a pleasant, aromatic odor.(herbicide); [NIOSH]
Sources/Uses
Used as a chemical intermediate, solvent, heat transfer liquid, deodorant, and insecticide; [ACGIH] Used as a degreasing agent, a paint solvent, paint remover, a cylinder lubricant, and a solvent for waxes, gums, resins, tars, rubber, oils, and asphalts; [HSDB]
Comments
Liver and kidney injury occur in animal inhalation studies. Inhalation of saturated vapor by mice results in narcosis and death. A case of skin sensitization reported, but "sufficient data were not available to recommend a SEN notation." [ACGIH] Inhalation of high concentrations may cause CNS effects; A skin, eye, and respiratory tract irritant; [ICSC]
Restricted
Cancelled: no registered pesticide products in the USA; [HSDB]
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Insufficient data
TLV (ACGIH)
25 ppm
STEL (ACGIH)
50 ppm
PEL (OSHA)
Ceiling(OSHA) = 50 ppm
MAK
10 ppm
IDLH (NIOSH)
200 ppm
Excerpts from Documentation for IDLHs
Basis for original (SCP) IDLH: The chosen IDLH is based on the statement by ACGIH [1971] that 1,000 ppm was fatal to guinea pigs after 20 hours [Browning 1953]. ACGIH [1971] also reported that Cameron et al. [1937] found liver damage in animals after exposure for a few hours at 50 to 800 ppm. . . . Human data: Concentrations up to 100 ppm have been reported to have caused sporadic irritation of the eyes and respiratory tract [Elkins 1959].
Vapor Pressure
1.36 mm Hg
Odor Threshold Low
0.02 ppm
Odor Threshold High
50 ppm
RD50
182 ppm
Lethal Concentration
LCLo (rat) = 821 ppm/7H
Explanatory Notes
Detection odor threshold from AIHA (mean = 0.70 ppm); Flash point = 151 deg F; VP from HSDB;
Reference Link #2
NFPA
high ambient temp required

Adverse Effects

Neurotoxin
Acute solvent syndrome
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Not classifiable
ACGIH Carcinogen
Not Classifiable

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: