o-Dichlorobenzene

Synonyms

1,2-Dichlorobenzene; Chloroben; Cloroben; DCB; Dichlorobenzene, ortho, liquid; Dilantin DB; Dilatin DB; Dizene; Dowtherm E; Orthodichlorobenzene; Orthodichlorobenzol; Special termite fluid; Termitkil; o-Dichlor benzol; o-Dichlorbenzol; o-Dichlorobenzene; o-Dichlorobenzol; [ChemIDplus] UN1591

Category

Chlorinated Aromatics

Description

Colorless to pale-yellow liquid with a pleasant, aromatic odor.(herbicide); [NIOSH]

Sources/Uses

Used as a chemical intermediate, solvent, heat transfer liquid, deodorant, and insecticide; [ACGIH] Used as a degreasing agent, a paint solvent, paint remover, a cylinder lubricant, and a solvent for waxes, gums, resins, tars, rubber, oils, and asphalts; [HSDB]

Comments

Liver and kidney injury occur in animal inhalation studies. Inhalation of saturated vapor by mice results in narcosis and death. A case of skin sensitization reported, but "sufficient data were not available to recommend a SEN notation." [ACGIH] Inhalation of high concentrations may cause CNS effects; A skin, eye, and respiratory tract irritant; [ICSC]

Cancelled: no registered pesticide products in the USA; [HSDB]

Biomedical References

Insufficient data

25 ppm

50 ppm

Ceiling(OSHA) = 50 ppm

10 ppm

200 ppm

Excerpts from Documentation for IDLHs

Basis for original (SCP) IDLH: The chosen IDLH is based on the statement by ACGIH [1971] that 1,000 ppm was fatal to guinea pigs after 20 hours [Browning 1953]. ACGIH [1971] also reported that Cameron et al. [1937] found liver damage in animals after exposure for a few hours at 50 to 800 ppm. . . . Human data: Concentrations up to 100 ppm have been reported to have caused sporadic irritation of the eyes and respiratory tract [Elkins 1959].

1.36 mm Hg

0.02 ppm

Odor Threshold High

50 ppm

182 ppm

LCLo (rat) = 821 ppm/7H

Explanatory Notes

Detection odor threshold from AIHA (mean = 0.70 ppm); Flash point = 151 deg F; VP from HSDB;

Reference Link #2

high ambient temp required

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Not classifiable

Not Classifiable

Diseases

Occupational diseases associated with exposure to this agent:

• Encephalopathy, chronic solvent
• Solvents, acute toxic effect

Processes

Industrial Processes with risk of exposure:

• Metal Degreasing
• Painting (Solvents)