Cocaine
Agent Name
Cocaine
CAS Number
50-36-2
Formula
C17-H21-N-O4
Major Category
Biological Agents
Synonyms
"C" Carrie; (1R,2R,3S,5S)-2-Methoxycarbonyltropan-3-yl benzoate; 1-Cocaine; 1-alpha-H,5-alpha-H-Tropane-2-beta-carboxylic acid, 3-beta-hydroxy-, methyl ester, benzoate; 2-beta-Carbomethoxy-3-beta-benzoxytropane; 2-beta-Tropanecarboxylic acid, 3-beta-hydroxy-, methyl ester, benzoate (ester); 2beta-Carbomethoxy-3beta-benzoxytropane; 3-(Benzoyloxy)-8-methyl-8-azabicyclo-(3.2.1)octane-2-carboxylic acid methyl ether; 3-Tropanylbenzoate-2-carboxylic acid methyl ester; 3beta-Hydroxy-1alphaH,5alphaH-tropane-2beta-carboxylic acid methyl ester benzoate; 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R-(exo,exo))-; Benzoylmethylecgonine; Bernice; Bernies; Blow; Burese; Cecil; Cholly; Cocaina; Cocaine, l-; Coke; Corine; Crack; Crack cocaine; Dama blanca; Ecgonine, methyl ester, benzoate (ester); Eritroxilina; Erytroxylin; Flake; Girl; Gold dust; Green gold; Happy dust; Happy trails; Her; Jam; Kokain; Kokan; Kokayeen; L-Cocaine; Lady; Leaf; Methyl 3-beta-hydroxy-1-alpha-H,5-alpha-H-tropane-2-beta-carboxylate benzoate (ester); Methyl 3beta-hydroxy-1alphaH,5alphaH-tropane-2beta-carboxylate benzoate (ester); Methyl Benzoylecgonine; Neurocaine; Nose candy; Pimp's drug; Rock; Snow; Star dust; Star-spangled powder; Toot; White girl or lady; [ChemIDplus]
Category
Plant Toxins
Description
Colorless to white solid; [Hawley]
Sources/Uses
Extracted from the leaves of coca shrubs indigenous to South America; Used as local anesthetic (nasal and ophthalmic) and vasoconstrictor for otolaryngology procedures; [HSDB] Used as a controlled substance in medicine and dentistry, usually as the hydrochloride compound; [Hawley] A popular drug of abuse; [Olson, p. 201]
Comments
CNS effects may include euphoria, delirium, agitation, muscle hyperactivity, and seizures. Cardiac effects may include arrhythmias, hypertension, hemorrhagic stroke, coronary artery spasm, and myocardial infarction. Death from overdose is usually due to fatal arrhythmias, status epilepticus, stroke, or hyperthermia. [Olson, p. 202-3] Use of cocaine during pregnancy is associated with premature birth, behavioral abnormalities of offspring, and possibly congenital anomalies of the urinary tract; [REPROTOX]
Biomedical References
Exposure Assessment
Vapor Pressure
1.91E-07 mm Hg
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Reproductive Toxin
Yes
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.