Coniine
Agent Name
Coniine
CAS Number
458-88-8
Formula
C8-H17-N
Major Category
Biological Agents
Synonyms
(+)-Coniine; (S)-(+)-Coniine; (S)-2-Propylpiperidine; (S)-Coniine; (S)-beta-Propylpiperidine; Cicutin; Cicutine; Conicine; Coniin; Koniin; Piperidine, 2-propyl-, (S)-; d-Conicine; [ChemIDplus]
Category
Plant Toxins
Description
Colorless liquid; Darkens and polymerizes upon exposure to light and air; [Merck Index]
Sources/Uses
Principle toxin of poison hemlock; [Merck Index]
Comments
Coniine from the poison hemlock (Conium maculatum) is a nicotine-like alkaloid that causes vomiting, pallor, and diaphoresis that usually resolves within 1-2 hours. In severe cases, patients have seizures and respiratory arrest. [Olson, p. 383, 337-8] Oral LD50 (mouse) = 100 mg/kg; [RTECS]
Biomedical References
Exposure Assessment
Vapor Pressure
0.693 mm Hg
Explanatory Notes
VP from ChemIDplus;
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.