Cupferron
Agent Name
Cupferron
CAS Number
135-20-6
Formula
C6-H6-N2-O2.H3-N
Major Category
Nitrogen Compounds
Synonyms
Ammonium N-nitrosophenylhydroxylamine; Ammonium cupferron; Ammonium nitroso-beta-phenylhydroxylamine; Ammonium-N-nitrosophenylhydroxylamine; Benzenamine, N-hydroxy-N-nitroso-, ammonium salt; Cupferon [Czech]; Cupferron, ammonium salt; Hydroxylamine, N-nitroso-N-phenyl-, ammonium salt; Kupferon; Kupferron [Czech]; N-Hydroxy-N-nitroso-benzenamine, ammonium salt; N-Nitroso-N-phenylhydroxylamine ammonium salt; N-Nitrosofenylhydroxylamin amonny [Czech]; N-Nitrosophenylhydroxylamin ammonium salz [German]; N-Nitrosophenylhydroxylamine ammonium salt; [ChemIDplus]
Category
Other Aromatics (Nitrogen)
Description
Creamy-white solid; [HSDB] Light yellow, cream-colored, or brown solid; Hygroscopic; [CAMEO] Pale yellow, odorless crystalline solid; [Alfa Aesar MSDS]
Sources/Uses
Used as an analytical reagent for separation and precipitation of metals and a quantitative reagent for vanadates, titanium, and colorimetric estimation of aluminum; [HSDB]
Comments
Emergency treatment: Methemoglobinemia; [HSDB] Causes various cancers when administered in the diet of rats; [NTP] A skin and eye irritant; May cause methemoglobinemia and liver damage; [CAMEO] A moderate eye irritant; Causes muscle weakness and dyspnea in oral lethal-dose studies of rats; [RTECS] A skin and serious eye irritant; Toxic if swallowed; Suspected carcinogen; [Aldrich MSDS] See 2021 (Volume 127) monograph at IARC.
Biomedical References
Exposure Assessment
Vapor Pressure
6.29E-05 mm Hg
Adverse Effects
Methemoglobinemia
MetHgb is secondary toxic effect
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Possible (2b)
NTP Carcinogen
Anticipated human carcinogen
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.