Dehydroheliotridine
Agent Name
Dehydroheliotridine
CAS Number
26400-24-8
Formula
C8-H11-N-O2
Major Category
Nitrogen Compounds
Synonyms
(+)-Dehydroheliotridine; 3,8-Dehydroheliotridine; 1H-Pyrrolizine-7-methanol, 2,3-dihydro-1-hydroxy-, (S)-; Heliotridine, 3,8-didehydro- (8CI); [ChemIDplus]
Category
Pyrroles
Sources/Uses
The major unbound metabolite of lasiocarpine and heliotrine (pyrrolizidine alkaloids found in the plant Heliotropium europaeum); [HSDB]
Comments
Growth retardation and teratogenic effects observed in embryos of rats administered 30-90 mg/kg by IP injection on day 14 of pregnancy and effects on embryo observed at day 20; Higher doses nearly stopped growth in many tissues; [HSDB] See "Heliotridine."
Biomedical References
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.