Di-n-butyltin dichloride

Synonyms

Chlorid di-n-butylcinicity [Czech]; Di-n-butyl-zinn-dichlorid [German]; Dibutyldichlorostannane; Dibutyldichlorotin; Dibutylstannium dichloride; Dibutyltin chloride; Dibutyltin dichloride; Dichlorodibutylstannane; Dichlorodibutyltin; Stannane, dibutyldichloro-; Tin, dibutyl-, dichloride; [ChemIDplus] UN3146

Category

Tin Compounds, Organic

Description

White solid; mp = 43 deg C; [Hawley] White paste with an acrid odor; mp = 39-41 deg C; [MSDSonline]

Sources/Uses

Used as organotin intermediate, a general-purpose stabilizers for polyvinyl chloride, an esterification catalyst, and a veterinary vermicide and tapeworm remedy; [HSDB]

Comments

In lethal dose studies by intravenous route, causes somnolence (general depressed activity), chronic pulmonary edema, and liver injury; Oral LD50 (rat) = 50 mg/kg; Intravenous LDLo (rat) = 10 mg/kg; [ChemIDplus] A strong skin and eye irritant; A potent immunotoxin--causes thymus lymphocyte depletion in animal experiments; [HSDB] A delayed skin, eye, and respiratory tract irritant; [INCHEM] Can cause burns; [eChemPortal: ESIS] May evolve hydrochloric acid on exposure to moisture; A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Can be absorbed through skin; [MSDSonline] See "Tin, organic compounds."

Biomedical References

Yes

0.1 mg/m3, as Sn

0.2 mg/m3, as Sn

0.1 mg/m3, as Sn

0.1 mg/m3, inhalable fraction, as Sn

25 mg/m3, as Sn

LC50 (rat) >364 mg/m3/4h

Explanatory Notes

VP = 2 mm Hg at 100 deg C; [HSDB] The Guide in the Emergency Response Guidebook is for "Organotin compound, solid, n.o.s." Organic tin compounds have a "skin" designation and are classified as "A4" (Not classifiable as human carcinogen); [ACGIH]

Other CNS neurotoxin

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Skin burns

Not Classifiable

Other Information

No other related information on this agent was found.