Diisooctyl phthalate

Agent Name
Diisooctyl phthalate
CAS Number
27554-26-3
Formula
C24-H38-O4
Major Category
Plastics & Rubber
Diisooctyl phthalate formula graphical representation
Synonyms
1,2-Benzenedicarboxylic acid, diisooctyl ester; Corflex 880; Di-iso-octyl phthalate; Diisooctyl 1,2-benzenedicarboxylate; DIOP; Flexol Plasticizer DIOP; Genomoll 100; Hexaplas M/O; Isooctyl phthalate; Phthalic acid, bis(6-methylheptyl)ester; Phthalic acid, diisooctyl ester; [ChemIDplus]
Category
Phthalate Esters
Description
Nearly colorless viscous liquid; [Hawley] Clear colorless viscous liquid; [MSDSonline]
Sources/Uses
Used as plasticizer for polyvinyl chloride jackets for building wire, cellulosic and acrylate resins, and synthetic rubber; Also used as a penetration agent for fungicides; Permitted for use as an additive in plastics in contact with food in Italy and the US; [HSDB]
Comments
There is confusion in the naming of the dioctyl phthalate esters: Di-n-octyl phthalate, Di-sec-octyl phthalate, and Diisooctyl phthalate. [CHEMINFO] Female mice fed >190 mg/kg/bw have weight loss and show increased resorptions, fetal malformations, and late fetal deaths; Mice fed 426 mg/kg/day show increased liver weight as well as reproductive effects; Oral LD50 (mouse) >26,000 mg/kg; Dioctyl phthalate may cause CNS depression and mild liver toxicity after ingestion of large amounts; [HSDB] No listed effects of short-term or long-term exposure; [ICSC] May cause irritation and liver damage; [MSDSonline] See "PHTHALATE ESTERS."
Biomedical References

Exposure Assessment

Vapor Pressure
5.5E-06 mm Hg
NFPA
must be preheated

Adverse Effects

Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Reproductive Toxin
Yes

Diseases, Processes, and Activities Linked to This Agent

Processes

Industrial Processes with risk of exposure: