Synonyms
Amid kyseliny mravenci [Czech]; Carbamaldehyde; Formamide; Formic acid, amide; Formimidic acid; Methanamide; Methanoic acid, amide; [ChemIDplus] UN8027
Description
Colorless, oily liquid. [Note: A solid below 37 degrees F.]; [NIOSH]
Sources/Uses
Used as a chemical intermediate and ionizing solvent; also used as a softener for glues, gums, and paper; [ACGIH]
Comments
Subchronic studies of rats exposed at 1500 ppm show decreased weight gain, kidney injury, and suppression of platelets and lymphocytes. By analogy with dimethylformamide, formamide is a suspected liver toxin. "No signs of toxicity were detected in rats exposed 6 hours/day for 10 days at approximately 100 ppm of formamide vapor (equivalent to air saturated with formamide at room temperature)." [ACGIH] A skin and eye irritant; Inhalation of high concentrations may cause CNS effects; [ICSC]
Skin Designation (ACGIH)
Yes
Vapor Pressure
0.061 mm Hg
Explanatory Notes
Flash point = 310 deg F; VP from HSDB;
Neurotoxin
Acute solvent syndrome
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
ACGIH Carcinogen
Confirmed Animal
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: