(E)-Crotonaldehyde

Agent Name
(E)-Crotonaldehyde
CAS Number
123-73-9
Formula
C4-H6-O
Major Category
Other Classes
(E)-Crotonaldehyde formula graphical representation
Synonyms
2-Butenal, (E)-; Aldehyde crotonique [French]; Crotonaldehyde, (E)-; (E)-2-Butenal; Topanel; Topanel CA; beta-Methyl acrolein; trans- Crotonal; trans-2-Butenal; trans-Crotonaldehyde; UN1143; [ChemIDplus]
Category
Aldehydes
Description
Water-white liquid with a pungent suffocating odor; [HSDB]
Sources/Uses
Used to make other chemicals (n-butyl alcohol, quinaldine, crotonic acid, 2-ethylhexyl alcohol, butyraldehyde, surface-active agents, resins, rubber antioxidants, textile and paper sizes, insecticides, and flavoring agents); Also used as a fuel-gas warning agent, solvent for polyvinyl chloride and purification of mineral oils, alcohol denaturant, leather tanning agent, to locate breaks and leaks in pipes, and in chemical warfare; [HSDB]
Comments
A mutagen and mild skin irritant; Causes ataxia in mice and convulsions in rats in lethal-dose inhalation studies; [RTECS] An eye, nose, pharynx, and larynx irritant; A lachrymator; [HSDB] A nasal membrane and strong eye irritant that may cause damage to the cornea; Causes lacrimation and may cause lung edema after inhalation of high concentrations; [CAMEO] A skin and respiratory tract irritant; May cause serious eye injury; [eChemPortal: ESIS] An irritant; Can be absorbed through skin; Effects in high-dose animal studies include lacrimation and convulsions; [MSDSonline] See "Crotonaldehyde."
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Yes
Ceiling (ACGIH)
0.3 ppm
PEL (OSHA)
2 ppm
Vapor Pressure
30 mm Hg
Odor Threshold Low
0.037 ppm
Odor Threshold High
1.05 ppm
Lethal Concentration
LC50 (rat) = 4,000 mg/m3/30min
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Crotonaldehyde, stabilized." Odor threshold from HSDB; VP from ChemIDplus;
NFPA
may ignite at ambient temp

Adverse Effects

Lachrymator
Yes
Neurotoxin
Other CNS neurotoxin

Diseases, Processes, and Activities Linked to This Agent

Processes

Industrial Processes with risk of exposure: