Ethylene glycol diacetate
Agent Name
Ethylene glycol diacetate
Alternative Name
EGD
CAS Number
111-55-7
Formula
C6-H10-O4
Major Category
Other Classes
Synonyms
EGD; 1,2-Diacetoxyethane; 1,2-Ethanediol diacetate; Aptex Donor H-plus; Ethanediol diacetate; Ethylene diacetate; Ethylene diethanoate; Ethylene glycol, diacetate; Glycol diacetate; [ChemIDplus] UN1993
Category
Ethylene Glycols
Description
Colorless liquid; [Hawley]
Sources/Uses
Used as solvent for oils, explosives, cellulose esters, cellulose ethers, natural products, printing inks, perfume fixatives, resins, and lacquers; Also used as a non-discoloring plasticizer for ethyl and benzyl cellulose; [HSDB] Used mainly as a re-flow solvent in thermoplastic acrylic coatings and in foundries (slow-release source of acetic acid for making cores); Also used as an ink solvent; [EPA ChAMP HPV: Ethylene glycol diacetate - 2002]
Comments
Its toxicity in animal experiments is thought to be due to metabolic conversion into ethylene glycol (EG); Animals poisoned with EGD have urinary oxalate crystals, an almost pathognomic sign of EG toxicosis; [EPA ChAMP HPV: Ethylene glycol diacetate - 2002] A mild eye irritant; [HSDB]; Causes general anesthesia in oral lethal-dose studies; Other adverse effects in multiple dose tests were changes in the blood and liver; [RTECS] Caused kidney stone formation and kidney damage in high-dose feeding studies of animals; [CHEMINFO] A mild skin irritant; [MSDSonline] See "Ethylene glycol."
Biomedical References
Exposure Assessment
Vapor Pressure
0.0774 mm Hg
Odor Threshold Low
0.093 ppm
Odor Threshold High
0.312 ppm
Explanatory Notes
Odor threshold low (absolute perception limit) and high (for both 50% and 100% recognition) from HSDB; The Guide in the Emergency Response Guidebook is for "Combustible liquid, n.o.s." VP from ChemIDplus;
NFPA
high ambient temp required
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Nephrotoxin
Yes
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: