Famphur

Synonyms

AC 38023; American Cyanamid CL-38,023; American Cyanamid-38023; BO-Ana; CL-38023; Dovip; ENT 25,644; Famfur; Famofos; Famophos; Famophos warbex; Famphos; Fanfos; O,O-Dimethyl O-(p-(N,N-dimethylsulfamoyl)phenyl) phosphorothioate; O,O-Dimethyl O-(p-(dimethylsulfamoyl)phenyl) phosphorothioate; O,O-Dimethyl phosphorothioate O-ester with p-hydroxy-N,N-dimethylbenzenesulfonamide (8CI); O-(4-(Dimethylamino)sulfonyl)phenyl) O,O-dimethyl phosphorothioate; O-(4-((Dimethylamino)sulfonyl)phenyl) O,O-dimethylphosphorothioate; O-4-Dimethylsulfamoylphenyl O,O-dimethyl phosphorothioate; O-4-Dimethylsulphamoylphenyl O,O-dimethyl phosphorothioate; Phosphorothioic acid, O,O-dimethyl ester, O-ester with p-hydroxy-N,N-dimethylbenzenesulfonamide; Phosphorothioic acid, O-(4-((dimethylamino)sulfonyl)phenyl) O,O-dimethyl ester; Warbex; Warbexol; p-Hydroxy-N,N-dimethylbenzenesulfonamide ester with phosphorothioic acid O,O-dimethyl ester; [ChemIDplus] UN2783

Category

Organophosphate Insecticides

Description

Colorless solid; [HSDB]

Sources/Uses

Used as veterinary insecticide for grubs and lice; [HSDB]

Comments

A cholinesterase inhibitor; [Hawley] Caused inhibition of cholinesterase activity in rats, birds, and livestock; [HSDB] A highly toxic cholinesterase inhibitor; [CAMEO] No adverse effects to fertility observed in cattle; No information found with regards to teratogenicity or effects on lactation; [REPROTOX] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]

Cancelled--no longer registered as a pesticide for use in the US; [HSDB]

Biomedical References

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

1.36E-06 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, solid, toxic."

Other Poison

Organophosphate

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)