Isopropyl acetate

Agent Name
Isopropyl acetate
CAS Number
108-21-4
Formula
C5-H10-O2
Major Category
Solvents
Isopropyl acetate formula graphical representation
Synonyms
1-Methylethyl acetate; 2-Acetoxypropane; 2-Propyl acetate; Acetate d'isopropyle [French]; Acetic Acid, isopropyl ester; Acetic acid, 1-methylethyl ester; Isopropile (acetato di) [Italian]; Isopropyl (acetate d') [French]; Isopropyl acetate; Isopropyl ethanoate; Isopropylacetaat [Dutch]; Isopropylacetat [German]; Isopropyle (acetate d') [French]; Isopropylester kyseliny octove [Czech]; Paracetat; [ChemIDplus] UN1220
Category
Esters (<C12)
Description
Colorless liquid with a fruity odor; [NIOSH]
Sources/Uses
Used as a solvent and flavoring agent; [ACGIH] Solvent uses include nitrocellulose, resins, paints, lacquers, inks, insecticides, and perfumes; [Hawley]
Comments
A skin, eye, and respiratory tract irritant; Inhalation of high concentrations far above the OEL can cause CNS depression; [ICSC]
Biomedical References

Exposure Assessment

PEL (OSHA)
250 ppm
MAK
100 ppm
IDLH (NIOSH)
1800 ppm
Excerpts from Documentation for IDLHs
Basis for original (SCP) IDLH: The chosen IDLH is based on the UCC [1970] report that a 4­hour exposure to 16,000 ppm killed 1 of 6 rats. . . . Other animal data: It has been stated that isopropyl acetate is comparable in toxicity to ethyl acetate and n­propyl acetate [ACGIH 1991]. \ Human data: None relevant for use in determining the revised IDLH.
Vapor Pressure
60.4 mm Hg
Odor Threshold Low
0.5 ppm
Odor Threshold High
34 ppm
Lethal Concentration
LC50 (rat) = 50,600 mg/m3/8H
Explanatory Notes
IDLH = 10% LEL; Detection odor threshold from AIHA (mean = 4.1 ppm); Flash point = 2 deg C; VP from HSDB; TLVs withdrawn; see Propyl acetate isomers; [ACGIH]
NFPA
may ignite at ambient temp

Adverse Effects

Neurotoxin
Acute solvent syndrome

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: