Geranyl acetate

Agent Name
Geranyl acetate
CAS Number
105-87-3
Formula
C12-H20-O2
Major Category
Other Classes
Geranyl acetate formula graphical representation
Synonyms
2,6-Octadien-1-ol, 3,7-dimethyl-, acetate; 3,7-Dimethyl-2,6-octadien-1-ol acetate; 2,6-Dimethyl-2,6-octadiene-8-yl acetate; 2,6-Octadien-1-ol, 3,7-dimethyl-, acetate, trans-; 2,6-Octadien-1-ol, 3,7-dimethyl-, acetate,(E)-; 3,7-Dimethyl-2,6-octadien-1-yl ethanoate, trans-; 3,7-Dimethyl-2-trans, 6-octadienyl acetate; Acetic acid, geraniol ester; Bay pine (oyster) oil; Geraniol acetate; Geranyl acetate (natural); Geranyl acetate A; trans-2,6-Dimethyl-2,6-octadien-8-yl ethanoate; trans-3,7-Dimethyl-2,6-octadien-1-ol, acetate; trans-3,7-Dimethyl-2,6-octadien-1-yl acetate; trans-Geraniol acetate; [ChemIDplus]
Category
Esters, Other
Description
Clear colorless liquid with a sweet odor like lavender; [HSDB]
Sources/Uses
Occurs in several essential oils; Used in perfumes and flavors; [Hawley]
Comments
A mutagen, tumorigen, and mild to severe skin irritant; Causes somnolence and coma in lethal-dose feeding studies of rats; Causes hepatitis and kidney injury in high-dose feeding studies of mice; [RTECS] Safe when used as a flavoring agent in food; ADI = 0-0.5 mg/kg bw; [JECFA] Slightly irritating to human skin; Effects in chronic feeding studies with rodents include cytoplasmic vacuolization of the liver, kidneys, and myocardium and lesions of the stomach; No evidence of carcinogenicity or mutagenicity; Emergency treatment: See "Citral" the active ingredient in lemon grass oil; [HSDB] A skin irritant; May cause eye injury; [CAMEO] Higher frequency of nephrosis observed in gavage study with rats (71% geranyl acetate and 29% citronellyl acetate in corn oil); Caused chromosomal aberrations in 2 of 3 bone marrow in vivo assays and mutations in mouse lymphoma assay; [EPA]
Biomedical References

Exposure Assessment

Vapor Pressure
0.033 mm Hg
Odor Threshold Low
0.009 ppm
Odor Threshold High
0.46 ppm
Explanatory Notes
Odor threshold (detection) = 9 - 460 ppb; [HSDB]
NFPA
must be preheated

Adverse Effects

Neurotoxin
Acute solvent syndrome
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: