Hexamethyldisiloxane
Agent Name
Hexamethyldisiloxane
CAS Number
107-46-0
Formula
C6-H18-O-Si2
Major Category
Metals
Synonyms
Belsil DM 0.65; Bis(trimethylsilyl)ether; Bis(trimethylsilyl)oxide; Bis-trimethylsilyl oxide; Bistrimethylsilyl ether; Disiloxane, hexamethyl-; Fluka AG; HMS; Hexamethyl disiloxane; KF 96L; OS 10; Oxybis(trimethylsilane); SWS-F 221; Silane, oxybis(trimethyl-; [ChemIDplus]
Category
Metalloid Compounds (Silicon)
Description
Liquid; [HSDB] Colorless liquid; [MSDSonline]
Sources/Uses
Used to make silicone fluids, elastomers, octamethylcyclotetrasiloxane, and fluorosilicone oils; Also used in cosmetics and in photolithography applications (adhesion promoter/priming agent); [HSDB]
Comments
An eye irritant; Oral LD50 (rat) = >5000 mg/kg; [HSDB] In a 28-day feeding study of rats, 8 mg/kg/day was the no toxic effect level; Food consumption was decreased and changes were seen in the liver and blood cells in animals fed 640 mg/kg/day; [TSCA Sub-Acute Oral Toxicity Study in Rats] May cause irritation; [MSDSonline]
Biomedical References
Exposure Assessment
Vapor Pressure
42 mm Hg
Lethal Concentration
LC50 (rat) = 15,956 ppm/4h
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.