Hymenoxone

Synonyms

Hymenoxon; Furo(2',3':5,6)cyclohepta(1,2-c)pyran-2(3H)-one, decahydro-5,7-dihydroxy-4a,9-dimethyl-3-methylene-, (3aR,4aS,5R,7R,8aR,9R,10aR)-; Furo(2',3':5,6)cyclohepta(1,2-c)pyran-2(3H)-one, decahydro-5,7-dihydroxy-4a,9-dimethyl-3-methylene-, (3aR-(3a-alpha,4a-beta,5-alpha,7-beta,8a-alpha,9-alpha,10a-alpha))-; [ChemIDplus]

Category

Plant Toxins

Sources/Uses

Toxic constituent of Hymenoxys odorata (bitterweed), Helenium hoopsii, and Baileya multiradiata (poisonous range plants); [HSDB]

Comments

Emergency treatment: "Plants- sesquiterpene lactones"; Sesquiterpene lactones are in many plants. They cause toxicity mainly in livestock that eat the plants. Human poisoning cases are extremely rare. Possible symptoms after ingestion include irritation of mucous membranes, dyspnea, pulmonary hemorrhage, tremors, seizures, abdominal pain, and liver injury. [HSDB] Sesquiterpene lactones are a common cause of allergic dermatitis in florists. See "Sesquiterpene lactones."

Biomedical References

Yes

Other CNS neurotoxin

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic