3,4-Dichlorophenyl isocyanate
Agent Name
3,4-Dichlorophenyl isocyanate
CAS Number
102-36-3
Formula
C7-H3-Cl2-N-O
Major Category
Toxic Gases & Vapors
Synonyms
1,2-Dichloro-4-isocyanatobenzene; 3,4-Dichlorfenylisokyanat [Czech]; Benzene, 1,2-dichloro-4-isocyanato-; Isocyanic acid, 3,4-dichlorophenyl ester; [ChemIDplus] UN2250
Category
Monoisocyanates
Description
White to yellow solid; [HSDB] White crystalline solid; [MSDSonline]
Sources/Uses
Used in organic synthesis; [Hawley]
Comments
An irritant that can cause acute inhalation injury; Acute pneumonitis is the most immediate serious effect after isocyanate exposure; [HSDB] Highly irritating to tissue; [CAMEO] May cause skin sensitization based on animal studies; [IUCLID] A lachrymator; [CHEMINFO] An irritant; A lachrymator; No sensitizing effects known; [MSDSonline] See "MONOISOCYANATES."
Biomedical References
Exposure Assessment
Lethal Concentration
LC50 (rat) = 2,700 mg/m3/4H
Explanatory Notes
Vapor pressure = 0.56 mm Hg at 43 deg C; [ChemIDplus] The Guide in the Emergency Response Guidebook is for "Dichlorophenyl isocyanates."
Adverse Effects
Lachrymator
Yes
Toxic Pneumonitis
Yes
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.