Isopropyl chloroformate
Agent Name
Isopropyl chloroformate
CAS Number
108-23-6
Formula
C4-H7-Cl-O2
Major Category
Toxic Gases & Vapors
Synonyms
Carbonochloride acid, 1-methylethyl ester; Carbonochloridic acid, 1-methylethyl ester; Chloroformic acid isopropyl ester; Formic acid, chloro-, isopropyl ester; Isopropyl chlorocarbonate; Isopropyl chloromethanoate; Isopropylester kyseliny chlormravenci [Czech]; [ChemIDplus] UN2407
Category
Acid Halides
Description
Clear liquid with an irritating odor; [CAMEO] Reacts with water evolving hydrogen chloride; [ICSC]
Sources/Uses
Used in organic synthesis; [CAMEO]
Comments
A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation can cause pulmonary edema; "Causes watering of the eyes." [ICSC] A skin, eye, and respiratory tract irritant; May cause pulmonary edema; [HSDB] See "CHLOROFORMATES."
Biomedical References
Exposure Assessment
TIH
Yes
Lethal Concentration
LCLo (rat) = 200 ppm/5h
Explanatory Notes
VP = 100 mm Hg at 47 deg C; [HSDB]
NFPA
may ignite at ambient temp
ERPG-1
Insufficient data
ERPG-2
5 ppm
ERPG-3
20 ppm
Adverse Effects
Lachrymator
Yes
Toxic Pneumonitis
Yes
Dermatotoxin
Skin burns
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: