Methylazoxymethanol
Agent Name
Methylazoxymethanol
CAS Number
590-96-5
Formula
C2-H6-N2-O2
Major Category
Biological Agents
Synonyms
1-Hydroxymethyl-2-methyldiimide-2-oxide; MAM; Methanol, (methyl-ONN-azoxy)-; [ChemIDplus]
Category
Plant Toxins
Sources/Uses
The biologically active aglycone of cycasin (toxic substance found in seeds of various Cycas plants); [HSDB]
Comments
Acts as biological methylating agent; Similar in action to carcinogenic N-nitroso compounds; Nervous system malformations, mental defects, and tumors seen in offspring of rats and hamsters injected during pregnancy; Evidence for carcinogenicity in experimental animals; [HSDB] A neuroteratogen; [ChemIDplus] Causes changes in recordings from specific areas of brain in intraperitoneal toxic-dose studies of rats; [RTECS]
Biomedical References
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Reproductive Toxin
Yes
IARC Carcinogen
Possible (2b)
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.