n-Propyl acetate

Synonyms

1-Acetoxypropane; 1-Propyl acetate; Acetate de propyle normal [French]; Acetic acid n-propyl ester; Acetic acid, propyl ester; Octan propylu [Polish]; Propyl acetate; Propyl ethanoate; Propylester kyseliny octove [Czech]; n-Propyl acetate; n-Propyl acetate (natural); n-Propyl ethanoate; [ChemIDplus] UN1276

Category

Esters (<C12)

Description

Colorless liquid with a mild, fruity odor; [NIOSH]

Sources/Uses

Used as a solvent, flavoring agent, and chemical intermediate; [ACGIH]

Comments

Esters may induce narcosis in animals, but workers' exposures are limited by irritating effects. See appendix in: [Dick RB, et al. Chemicals in the workplace: incorporating human neurobehavioral testing into the regulatory process. Am J Ind Med. 1998 May;33(5):439-53.] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]

Biomedical References

Insufficient data

100 ppm

150 ppm

200 ppm

100 ppm

1700 ppm

Excerpts from Documentation for IDLHs

Basis for original (SCP) IDLH: The chosen IDLH is based on the statement by ACGIH [1971] that a 4­hour exposure to 8,000 ppm was fatal to 4 of 6 rats [Smyth et al. 1954]. . . . Human data: None relevant for use in determining the revised IDLH.

35.9 mm Hg

0.04 ppm

Odor Threshold High

0.7 ppm

LCLo (rat) = 8,000 ppm/4H

Explanatory Notes

Detection odor threshold from AIHA (mean = 0.18 ppm); Flash point = 14 deg C; VP from HSDB;

may ignite at ambient temp

Acute solvent syndrome

Diseases

Occupational diseases associated with exposure to this agent:

• Encephalopathy, chronic solvent
• Solvents, acute toxic effect

Processes

Industrial Processes with risk of exposure:

• Painting (Solvents)
• Plastic Composites Manufacturing