N,N,N',N'-Tetramethyl-1,2-ethanediamine

Agent Name
N,N,N',N'-Tetramethyl-1,2-ethanediamine
CAS Number
110-18-9
Formula
C6-H16-N2
Major Category
Nitrogen Compounds
N,N,N',N'-Tetramethyl-1,2-ethanediamine formula graphical representation
Synonyms
1,2-Bis-(dimethylamino)ethane; 1,2-Ethanediamine, N,N,N',N'-tetramethyl-; Dimethyl(2-(dimethylamino)ethyl)amine; Ethylenediamine, N,N,N',N'-tetramethyl-; N,N,N',N'-Tetramethyl-1,2-diaminoethane; N,N,N',N'-Tetramethylethanediamine; N,N,N',N'-Tetramethylethylenediamine; Propamine D; TMEDA; TEMED; Tetrameen; Tetramethyl ethylene diamine; Tetramethyldiaminoethane; Tetramethylethylenediamine; 1,2-Di-(dimethylamino)ethane; [ChemIDplus] UN2372
Category
Amines, Aliphatic
Description
Colorless liquid with a mild odor of ammonia; [HSDB] Hygroscopic; [CHEMINFO]
Sources/Uses
Used to make epoxy curing agents, polyurethane, and quaternary ammonium compounds; Also used in textile finishing agents, as a corrosion inhibitor, acrylamide polymerization catalyst, and reagent; [HSDB] Used as polymerization accelerator in gel electrophoresis, a solvent, and an oxidizing reagent; [Merck Index]
Comments
Emergency treatment: Irritants; [HSDB] Corrosive to skin and eyes, based on animal studies; [CHEMINFO] Highly flammable; Can cause burns; [eChemPortal: ESIS] Necrosis observed 14 days following three minute exposure to rabbit skin; Severe eye irritant in rabbits; Lesions of the brain observed in oral lethal-dose study of rats; No evidence of mutagenicity; [EPA HPVIS] Causes burns; Toxic by ingestion; May be absorbed through skin; If inhaled may cause corrosive effects to upper respiratory tract and lungs; [Aldrich MSDS]
Biomedical References

Exposure Assessment

Vapor Pressure
16.7 mm Hg
Odor Threshold Low
0.1 ppm
Lethal Concentration
LC50 (rat) = 1,318 ppm/4h
Explanatory Notes
Odor threshold (unspecified) from CHEMINFO; VP from ChemIDplus;

Adverse Effects

Toxic Pneumonitis
Yes
Dermatotoxin
Skin burns

Diseases, Processes, and Activities Linked to This Agent

Processes