N-Isopropylacrylamide
Agent Name
N-Isopropylacrylamide
CAS Number
2210-25-5
Formula
C6-H11-N-O
Major Category
Nitrogen Compounds
Synonyms
2-Propenamide, N-(1-methylethyl)-; Acrylamide, N-isopropyl-; Isopropyl acrylamide; Isopropylamid kyseliny akrylove [Czech]; N-(1-Methylethyl)-2-propenamide; Nipam; [ChemIDplus]
Category
Other Nitrogen Compounds
Description
Solid; [Hawley]
Sources/Uses
Used in binders for textiles, paper, adhesives, detergents, and cosmetics; [Hawley]
Comments
Crude solutions may cause skin irritation; Causes hind quarter paralysis and head tremors in cats administered intraperitoneally at total cumulative dose of 840 mg/kg over 18 day period (fully recovered after five weeks); Testicular atrophy (degeneration of epithelial cells of the seminiferous tubules) observed in mice following repeated oral doses; [HSDB] A moderate eye irritant; Causes spastic paralysis and hemorrhage in dermal lethal-dose study of rabbits and oral lethal-dose study or rats; Causes changes in testicular weight in eight week intermittent oral study of mice; [RTECS] An irritant; [Aldrich MSDS]
Biomedical References
Exposure Assessment
Vapor Pressure
0.023 mm Hg
Explanatory Notes
VP from ChemIDplus;
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Diseases, Processes, and Activities Linked to This Agent
Processes
Industrial Processes with risk of exposure: