N(1)-Acetylphenylhydrazine
Agent Name
N(1)-Acetylphenylhydrazine
CAS Number
114-83-0
Formula
C8-H10-N2-O
Major Category
Nitrogen Compounds
Synonyms
1-Acetyl-2-phenylhydrazine; 1-Phenyl-2-acetylhydrazine; APH; Acetic acid phenylhydrazone; Acetylphenylhydrazine; Fenylhydrazid kyseliny octove [Czech]; Hydracetin; N'-Phenylacethydrazide; N-Acetyl-N'-phenylhydrazine; Pyrodin; Pyrodine; beta-Acetylphenylhydrazine; [ChemIDplus]
Category
Hydrazides
Description
Colorless or white solid; [CAMEO] Off-white powder; [MSDSonline]
Sources/Uses
Used as an intermediate for pharmaceuticals and other chemicals; Formerly used to treat polycythemia; [HSDB]
Comments
Emergency treatment: "Hydrazines"; Hydrazines can cause severe eye damage. They can cause seizures, liver injury, hemolysis, and delayed pulmonary edema. [HSDB] Oral LD50 (mouse) = 270 mg/kg; Causes methemoglobinemia in feeding studies of dogs; [RTECS] An irritant; [MSDSonline] See "Hydrazine."
Biomedical References
Exposure Assessment
Vapor Pressure
7.3E-05 mm Hg
Adverse Effects
Methemoglobinemia
MetHgb is secondary toxic effect
Neurotoxin
Other CNS neurotoxin
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.