N,N-Dimethyl-N-dodecylamine oxide

Agent Name
N,N-Dimethyl-N-dodecylamine oxide
Alternative Name
Lauramine oxide
CAS Number
1643-20-5
Formula
C14-H31-N-O
Major Category
Other Uses
N,N-Dimethyl-N-dodecylamine oxide formula graphical representation
Synonyms
Lauramine oxide; Lauryl dimethyl amine oxide; N,N-Dimethyl-1-dodecanamine-N-oxide; 1-Dodecanamine, N,N-dimethyl-, N-oxide; Ammonyx AO; Ammonyx LO; Amonyx AO; Aromox DMCD; Aromox dmmc-W; Conco XAL; DDNO; Dimethylaurylamine oxide; Dimethyldodecylamine N-oxide; Dimethyldodecylamine oxide; Dimethyllaurylamine oxide; Dodecylamine, N,N-dimethyl-, N-oxide; Dodecyldimethylamine N-oxide; Dodecyldimethylamine oxide; Empigen OB; Lauryldimethylamine N-oxide; Lauryldimethylamine oxide; N,N-Dimethyl-dodecylaminoxid [Czech]; N,N-Dimethyldodecylamine oxide; N-Lauryl-N,N-dimethylamine oxide; N-Lauryldimethylamine N-oxide; Oxyde de dimethyllaurylamine [French]; Refan [Russian]; n-Dodecyldimethylamine oxide; [ChemIDplus] UN3259
Category
Emulsifiers/Surfactants
Description
Highly hygroscopic solid; [HSDB]
Sources/Uses
Used as a foam builder and stabilizer; Used in cosmetics, emollients, conditioners, emulsifiers, dishwasher detergents, shampoos, soaps, and antistatic, wetting, antibacterial, and antifungal agents; [HSDB]
Comments
Caused severe skin irritation (including severe erythema and edema, fissuring with bleeding, and necrosis) in rabbit studies; High dose animal feeding studies produced no significant adverse effects; [HSDB] Amine oxides are metabolized and rapidly excreted after ingestion; Effects on skin are: 1% solutions not irritating, 5% solutions moderately irritating, and 30% solutions severely irritating; No evidence of skin sensitization; No evidence of carcinogenic response or reproductive toxicity; [OECD SIDS] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; [MSDSonline]
Biomedical References

Exposure Assessment

Vapor Pressure
6.23E-08 mm Hg
Lethal Concentration
LC50 (rat) = 5.3 g/mL/4h (aerosol of 0.3% lauramine oxide;
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Amines, solid, corrosive, n.o.s."

Adverse Effects

Toxic Pneumonitis
Yes
Dermatotoxin
Skin burns

Diseases, Processes, and Activities Linked to This Agent

Processes

Industrial Processes with risk of exposure: