1,1,2,2-Tetrachloro-1,2-difluoroethane
Agent Name
1,1,2,2-Tetrachloro-1,2-difluoroethane
Synonyms
1,2-Difluoro-1,1,2,2-tetrachloroethane; CFC-112; Daiflon 112; Daiflon S2; F-112; FC 112; Fluorocarbon 112; Freon 112; Freon R 112; Genetron 112; Halocarbon 112; R 112; Refrigerant 112; Tetrachloro-1,2-difluoroethane; Ucon 112; sym-Tetrachlorodifluoroethane; [ChemIDplus]
Category
Chlorofluorocarbons
Description
Colorless solid or liquid (above 77 degrees F) with a slight, ether-like odor; [NIOSH]
Sources/Uses
CFC-112 has been used mainly as a refrigerant. [ACGIH]
Comments
Rats exposed to 10,000 ppm for 2 hours show signs of intoxication. Exposure to 20,000 to 30,000 ppm for 1 to 2.5 hours causes fatal pulmonary hemorrhages. It is concluded that CFC-112 at concentrations of 1% (10,000 ppm) or more is a pulmonary irritant. [ACGIH] See "CHLOROFLUOROCARBONS"
Restricted
See CHLOROFLUOROCARBONS
Skin Designation (ACGIH)
Insufficient data
Excerpts from Documentation for IDLHs
Other animal data: Rats exposed to 10,000 ppm for 1.5 to 2 hours showed slight signs of intoxication but no loss of reflexes, while 20,000 to 30,000 ppm was fatal in 1.0 to 2.5 hours [Greenberg and Lester 1950].
Vapor Pressure
50.5 mm Hg
Lethal Concentration
LC50 (rat) = 20,000 ppm/15 min
Explanatory Notes
mp = 26 deg C; bp = 92.8 deg C; Thermal decomposition products include HCl, HF, and phosgene; [ACGIH] VP from HSDB;
Neurotoxin
Acute solvent syndrome
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases
Occupational diseases associated with exposure to this agent: