p-Chloroacetanilide
Agent Name
p-Chloroacetanilide
CAS Number
539-03-7
Formula
C8-H8-Cl-N-O
Major Category
Nitrogen Compounds
Synonyms
4-Chloroacetanilide; Acetamide, N-(4-chlorophenyl)-; Acetanilide, 4'-chloro-; Acetic acid, amide, N(4-chlorophenyl)-; Acetic-4-chloroanilide; N-(4-Chlorophenyl)acetamide; N-(p-Chlorophenyl)acetamide; N-Acetyl-p-chloroaniline; [ChemIDplus]
Category
Other Aromatics (Nitrogen)
Description
Solid; [HSDB] White or light brown powder; [Alfa Aesar MSDS]
Sources/Uses
A soil bacteria metabolite of 4-chloroaniline and contaminant of phenacetin; Used as research chemical; Not commercially produced in the US; [HSDB]
Comments
Causes Heinz body formation, hemolysis, and spleen enlargement in rats; Exhibits nephrotoxic and hepatotoxic potential in intraperitoneal studies of rats; [HSDB] Causes decreased body temperature in intraperitoneal lethal-dose studies of rats; [RTECS] A skin and strong eye irritant; [Alfa Aesar MSDS] See "Acetanilide."
Biomedical References
Exposure Assessment
Vapor Pressure
9.63E-05 mm Hg
Adverse Effects
Methemoglobinemia
MetHgb is secondary toxic effect
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.