Pentachlorodibenzo-p-dioxin
Agent Name
Pentachlorodibenzo-p-dioxin
CAS Number
36088-22-9
Formula
C12-H3-Cl5-O2
Major Category
Other Classes
Synonyms
Dibenzo(b,e)(1,4)dioxin, pentachloro-; [ChemIDplus]
Category
Halogenated Polyaromatics
Sources/Uses
Released to the environment in emissions from wood combustion, waste oil furnaces, fires of materials containing PVC, fires of electrical equipment containing polychlorinated biphenyls (PCBs), and cigarette smoke; Found in 2,4,5-T and other pesticides; Released in effluents from the pulp and paper industries, and in municipal sewage; Can be produced by thermal and chemical degradation of chlorophenols; [HSDB]
Comments
IARC classification is for polychlorinated dibenzo-para-dioxins other than 2,3,7,8-Tetrachlorodibenzo-p-dioxin; Polychlorodibenzodioxins have caused chloracne in humans; Occupational exposure may occur in metal reclamation, during use or manufacture of chlorophenol, or during herbicide manufacture; Oral LD50 (rat) = 0.206 mg/kg for the 1,2,3,7,8- isomer; [HSDB] See "2,3,7,8-Tetrachlorodibenzo-p-dioxin."
Biomedical References
Exposure Assessment
Vapor Pressure
5.6E-10 mm Hg
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Dermatotoxin
Chloracne
ACGIH Carcinogen
Not Classifiable
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: