Tri-m-cresyl phosphate
Agent Name
Tri-m-cresyl phosphate
Alternative Name
Trimetacresyl phosphate
CAS Number
563-04-2
Formula
C21-H21-O4-P
Major Category
Other Classes
Synonyms
Phosphoric acid tri-m-tolyl ester; Phosphoric acid, tri(3-tolyl)ester; Phosphoric acid, tris(3-methylphenyl) ester; Tri-m-tolyl phosphate; Tris(m-tolyl) phosphate; Tris-m-cresyl phosphate; [ChemIDplus] UN2574
Category
Organophosphates, Other
Description
Wax; mp = 25.5 deg C; [HSDB] Slightly yellow to pink clear liquid; [MSDSonline]
Sources/Uses
Used in a isomeric mixture known as Tricresyl phosphate (CAS # 1330-78-5); No uses for the isolated isomer; [HSDB]
Comments
Permanent paralysis reported in worker involved in manufacture of meta and para isomers; Mildly toxic to animals; Six times less toxic than the ortho isomer; Emergency treatment: "TOCP and related agents"; [HSDB] A metabolite of the ortho isomer (TOCP) caused "ginger jake paralysis," a motor neuropathy. See "Triorthocresyl phosphate," Tri-p-cresyl phosphate," and "Tricresyl phosphate (mixed isomers)." TLV Basis includes adrenal gland and female reproductive system damage. [ACGIH TLVs and BEIs]
Biomedical References
Exposure Assessment
Vapor Pressure
1.09E-07 mm Hg
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Tricesyl phosphate." See 2024 "Notice of Intended Changes" for TLV; [ACGIH TLVs and BEIs]
Adverse Effects
Reproductive Toxin
Yes
Other Poison
Organophosphate
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: