Proflavine
Agent Name
Proflavine
CAS Number
92-62-6
Formula
C13-H11-N3
Major Category
Other Uses
Synonyms
2,8-Diaminoacridine (European); 2,8-Diaminoacridinium; 3,6-Diaminoacridine; 3,6-Diaminoacridinium; 3,7-Diamino-5-azaanthracene; Isoflav base; Proflavin; Proflavina [INN-Spanish]; Proflavinum [INN-Latin]; 3,6-Acridinediamine; Acridine, 3,6-diamino-; [ChemIDplus]
Category
Biocides/Disinfectants
Description
Yellow solid; [Merck Index]
Sources/Uses
Used as a topical antiseptic; [Merck Index] Proflavine impregnated wool is used by some UK plastic surgeons; [HSDB] Used in the treatment of psoriasis and herpesvirus infections; [NTP]
Comments
Proflavine and its salts are used as topical antiseptics; No epidemiological studies available and animal data inadequate for evaluation; [IARC] Allergic contact dermatitis has been reported; [HSDB] Intraperitoneal LD50 (mouse) = 50 mg/kg; [Sax] An irritant; [MSDSonline]
Biomedical References
Exposure Assessment
Vapor Pressure
8.94E-08 mm Hg
Adverse Effects
IARC Carcinogen
Not classifiable
Diseases, Processes, and Activities Linked to This Agent
Processes
Industrial Processes with risk of exposure: