Quinoline

Synonyms

1-Azanaphthalene; 1-Benzazine; 2,3-Benzopyridine; B 500; B-500; Benzo(b)pyridine; Benzopyridine; Benzopyridine (VAN); Chinoleine; Chinolin [Czech]; Chinoline; Leucol; Leukol; Quinolin; [ChemIDplus] UN2656

Category

Quinolines

Description

Colorless hygroscopic liquid with characteristic odor; Turns brown after exposure to light; [ICSC] Clear liquid that darkens as ages; [Hawley] Light yellow liquid; [MSDSonline]

Sources/Uses

Used to make paints, dyes, and other chemicals; Also used as a preservative for anatomical specimens, solvent for resins and terpenes, fungistat, corrosion inhibitor, antimalarial drug, flavoring agent, and decarboxylation reagent; [HSDB] Extracted from coal-tar distillates; occurs in polluted air and cigarette smoke; [AIHA]

Comments

A skin and eye irritant; May have effects on the liver and retina; Possibly carcinogenic in humans; [ICSC] Causes lethargy, respiratory depression, and coma in high-dose animal experiments; No rats died when exposed to saturated vapor (about 78 ppm) for 8 hours, but all rats died within 6 hours after exposure to 4000 ppm; [HSDB] An irritant; May cause serious injury to eyes; Can be absorbed through skin; [MSDSonline]

Biomedical References

0.06 mm Hg

71 ppm

Explanatory Notes

Flash point = 105 deg C; [ICSC] Odor threshold from HSDB; VP from ChemIDplus;

high ambient temp required

0.001 ppm

Other CNS neurotoxin

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Possible (2b)

Processes

Industrial Processes with risk of exposure:

• Using Disinfectants or Biocides