Synonyms
Rapamycin; (-)-Rapamycin; (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone; AY 22989; Antibiotic AY 22989; Rapammune; Rapamune; SILA 9268A; [ChemIDplus]
Comments
Emergency treatment: "Tacrolimus and related agents"; May cause tremors and seizures; Other adverse effects in treated patients include diarrhea, kidney injury, anemia, thrombocytopenia, rash, and hypertension. Acute overdoses of up to 120 mg are generally well tolerated in adults. [HSDB] May cause irritation; Targets the immune system; [MSDSonline]