Tebupirimfos

Synonyms

BAY-MAT 7484; MAT 7484; O-(2-(1,1-Dimethylethyl)-5-pyrimidinyl) O-ethyl O-(1-methylethyl) phosphorothioate; Phostebupirim; Tebupirimphos; Phosphorothioic acid, O-(2-(1,1-dimethylethyl)-5-pyrimidinyl) O-ethyl O-(1-methylethyl) ester; [ChemIDplus] UN3018

Category

Organophosphate Insecticides

Description

Amber to brown liquid; [HSDB] Colorless to amber liquid; [MSDSonline]

Sources/Uses

Used as insecticide for soil insects in corn; [HSDB]

Comments

In a study with rats, reproductive effects (decrease in fertility and increase in dead pups) but no teratogenic effects were observed at doses maternally toxic; No evidence of mutagenicity; [HSDB] “Not Likely” to be carcinogenic to humans based on studies with rats and mice; [Reference #1] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]

Restricted use classification; [Reference #1]

Reference Link #1

Biomedical References

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

3.75E-05 mm Hg

LC50 (rat) = 36 mg/m3/4H

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, liquid, toxic."

Other Poison

Organophosphate

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)