Diaminotoluene, mixed isomers

Synonyms

Toluenediamine, mixed isomers; Toluene-ar,ar'-diamine; Methylphenylenediamine; Phenylenediamine, ar-methyl-; TDA 8020; Toluenediamine; Tolylenediamine; Benzenediamine, ar-methyl-; [ChemIDplus] UN1709

Category

Amines, Aromatic

Description

White, yellow, or tan solid with an ammonia-like odor; Darkens upon exposure to light and air or upon extended storage, turning deep violet or black; [CHEMINFO] Light yellow solid; [MSDSonline]

Sources/Uses

Used as a chemical intermediate in the preparation of fungicides; [HSDB] There are 6 isomers of TDA, but only 2,4-, 2,5-, and 2,6-TDA are of commercial interest; Used to make toluene diisocyanate; [AIHA]

Comments

A skin sensitizer; May cause lacrimation and chemosis in the eyes; [HSDB] No skin sensitization was detected in a study of 31 human volunteers; May stain skin yellow; [AIHA] May cause irritation; May induce methemoglobinemia; Can be absorbed through skin; Acute overexposure may cause liver and kidney injury and anemia; [MSDSonline] See "2,4-Diaminotoluene" and "2,5-Diaminotoluene."

Biomedical References

0.0014 mm Hg

Explanatory Notes

Flash Point = 140 deg C; [CHEMINFO] The Guide in the Emergency Response Guidebook is for "2,4-Toluenediamine."

0.005 ppm

Yes

Yes

MetHgb is secondary toxic effect

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic