Tonalid
Agent Name
Tonalid
CAS Number
21145-77-7; 1506-02-1
Formula
C18-H26-O
Major Category
Other Classes
Synonyms
2'-Acetonaphthone, 5',6',7',8'-tetrahydro-3',5',5',6',8',8'-hexamethyl-; AHMT; AHMT (perfume); AHTN; Musk tonalid; Tentarome; Tetralide; Tonalide; 1-(5,6,7,8-Tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one; Ethanone, 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl)-; [ChemIDplus]
Category
Aromatic Ketones
Description
Solid with an odor of musk; [HSDB]
Sources/Uses
Used as fragrance for cosmetics, detergents, fabric softeners, household cleaning products, and air fresheners; [HSDB]
Comments
A mild eye irritant, based on animal studies; [CHEMINFO] Causes liver injury in high-dose animal experiments; [RTECS] May be safely used as a fragrance in cosmetics up to 12%; [European Commission] Included in list of "fragrance substances with negative human data, i.e. patch tests of patients with suspected contact allergy to fragrance ingredients which yielded negative results."; [EC: Scientific Committee on Consumer Safety: Fragrance allergens in cosmetic products (2011)] May cause irritation; [MSDSonline]
Biomedical References
Exposure Assessment
Vapor Pressure
0.000512 mm Hg
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.