Methyl isopropyl ketone
Agent Name
Methyl isopropyl ketone
CAS Number
563-80-4
Formula
C5-H10-O
Major Category
Solvents
Synonyms
2-Acetyl propane; 2-Acetylpropane; 2-Methyl-3-butanone; 3-Methyl-2-butanone; Isopropyl methyl ketone; Ketone, isopropyl methyl; MIPK; Methyl butanone-2; Methyl isopropyl ketone; Methylbutanone (VAN); 2-Butanone, 3-methyl-; 3-Methylbutanone; 3-Methylbutan-2-one; [ChemIDplus] UN2397
Category
Ketones (<C12)
Description
Colorless liquid with an acetone-like odor; [Merck Index]
Sources/Uses
A pyrolysis product from hot gas welding of PVC plastic; [ACGIH]
Comments
A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC] An irritant; [MSDSonline] Causes narcosis in experimental animals fed high doses by oral gavage; TLV Basis is toxicity to embryo, fetus, and newborn; [ACGIH]
Biomedical References
Exposure Assessment
Skin Designation (ACGIH)
Insufficient data
TLV (ACGIH)
20 ppm
Vapor Pressure
52.2 mm Hg
Odor Threshold Low
1.9 ppm
Odor Threshold High
4.8 ppm
Lethal Concentration
LCLo (rat) = 5,700 ppm/4h
Explanatory Notes
Flash point = -1 deg C; [ICSC] Odor threshold from CHEMINFO; VP from ChemIDplus;
Adverse Effects
Neurotoxin
Acute solvent syndrome
Reproductive Toxin
Yes
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: