Tetrachlorophthalic anhydride

Synonyms

1,3-Dioxy-4,5,6,7-tetrachloroisobenzofuran; 1,3-Isobenzofurandione, 4,5,6,7-tetrachloro-; 4,5,6,7-Tetrachloro-1,3-isobenzofurandione; CP 626; Niagathal; Phthalic anhydride, tetrachloro-; Tetrathal; [ChemIDplus] TCPA; [HSDB]

Category

Acid Anhydrides, Cyclic

Description

White odorless solid; [Hawley] Light gray crystalline solid; [Aldrich MSDS]

Sources/Uses

Used as flame retardant in unsaturated polyester resins, polyurethane foams, and surface coatings; also used as a chemical intermediate for pigments, drugs, and plasticizers; [HSDB] May contain hexachlorobenzene as an impurity; [ExPub: CPS&Q]

Comments

Occupational asthma reported in workers manufacturing epoxy resins and plastics; [Malo] Produces the acid on reaction with water; A skin, eye, and respiratory tract irritant; May cause skin sensitization and asthma; [ICSC] Causes kidney and blood changes in gavage studies of rats and lung changes in inhalation studies of rats; [EPA ChAMP] See "ACID ANHYDRIDES."

Reference Link #1

Biomedical References

LC50 (rat) > 3,600 mg/m3/4hr

Yes

Yes

Diseases

Occupational diseases associated with exposure to this agent:

• Asthma, occupational
• Contact dermatitis, allergic

Processes

Industrial Processes with risk of exposure:

• Plastic Composites Manufacturing