Colophony

Agent Name
Colophony
CAS Number
8050-09-7
Major Category
Biological Agents
Synonyms
Abeitic acid; Tall oil; Abitol; Gum rosin; Rosin gum; W-W wood rosin; Abietic alcohol; Abietyl alcohol; Dercolyte ZS; Dertomal 18; Dertophene 18; Foral 105; Granolite SG; Hercolyn D; Methyl abietate alcohol; Resina terebinthinae; Staybelite 10; [Marks] Rosin; Disproportionated rosin; Gum rosin; Wood rosin; Pine rosin; Rosin Solder Flux Fume; [ChemFinder] Gum rosin; Rosin gum; WW Wood rosin; BALS 3A; Bandis G100; Colophonium; EM 3; Highrosin; Hongkong rosin WW; KE 709; Kolophonium; Rondis R; Rosin; Rosin WW; Shiragiku rosin; Yellow resin; Rosin core solder thermal decomposition products, as resin acids-colophony; [ChemIDplus] Synonyms for Resin acids are Rosin, Colophony, Gum rosin, Tall oil rosin, Wood rosin, Rosin core thermal decomposition products, and Yellow resin; [ACGIH 2020]
Category
Rosin and Derivatives
Description
Light yellow to amber solid; [ICSC]
Sources/Uses
Allergic contact dermatitis in construction workers, house painters, shoemakers, electronics workers, machinists, and mechanics; [Marks] Colophony was thought to be the allergen in a case of occupational rhinitis caused by Nobetec, used by dentists to make temporary dental fillings. [Int Arch Occup Environ Health 2002;75:209-16] Used in the finishing stage of leather production; [PMID 21938525]
Comments
Gum rosin, the most common type of colophony, is derived from living pine trees. Wood rosin and tall oil rosin are other types of colophony. Abietic acid is the active allergen present in colophony. [Marks, p. 80] Other allergens found in soldering fluxes include aminoethylethanolamine and hydrazine. Aminoethylethanolamine-based solders are commonly used in printed circuit board soldering. [Marks, p. 318] Skin sensitization to colophony allergens is common. It is not possible to patch test for all of the allergens in colophony. Since colophony allergens are present in many products at work and at home, it may be difficult to avoid exposure. There are three types of colophony (rosin) depending on the method of recovery: gum rosin, wood rosin, and tall oil rosin. Resinates are salts formed by the reaction of resin acids with metal salts. "The paper industry uses large amounts of rosin for paper size, that is, to give the paper a smooth and hydrophobic surface." [Kanerva, p. 467-77] Colophony (tall oil) can cause asthma in workers manufacturing rubber tires, soldering flux, and electronics; [Malo] "Colophony (rosin) can induce allergic contact dermatitis (including airborne type) and immunological contact urticaria." [Kanerva, p. 697] See "Rosin core solder thermal decomposition products (colophony)." See "Tall-oil rosin."
Biomedical References

Exposure Assessment

TLV (ACGIH)
0.001 mg/m3, as total resin acids, inhalable particulate matter
Reference Link #2

Adverse Effects

Skin Sensitizer
Yes
Asthma
Yes

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent:

Activities

Activities with risk of exposure: