2,7-Naphthalenediol

Agent Name
2,7-Naphthalenediol
CAS Number
582-17-2
Formula
C10-H8-O2
Major Category
Other Classes
2,7-Naphthalenediol formula graphical representation
Synonyms
2,7-Dihydroxynaphthalene; C.I. 76645; CI 76645; Naphthalene-2,7-diol; Naphthalenediol-2,7 [French]; [ChemIDplus]
Category
Naphthols
Description
Light grey or slightly yellow solid; [EC: Opinion of the SCCP on 2,7-naphthalenediol] Grey powder; [Alfa Aesar MSDS]
Sources/Uses
Used in oxidative hair dye formulations; [EC: SCCP]
Comments
Not irritating to rabbit skin; Highly irritating and corrosive to rabbit eyes; A moderate skin sensitizer using the mouse local lymph node assay (LLNA); Changes in hematology (reduced hemoglobin in males and higher MCV and MCH values in females), clinical chemistry (increased GGT in males and ALT in females), and histopathological changes in liver and kidney observed in 90-day oral study of rats; Hematological changes and histopathology of liver and kidney reversed within four week recovery period; No evidence of teratogenicity in rats; Not likely to have mutagenic potential in vivo; [EC: SCCP] A skin and strong eye irritant; [Alfa Aesar MSDS] See "1-Napththol" and "2-Naphthol."
Biomedical References

Adverse Effects

Skin Sensitizer
Yes
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: