Table 1--Chemicals that Cause Occupational Allergic Contact Dermatitis
| Agent Name | CAS # | Other Names |
|---|---|---|
| Acrylates & Methacrylates | ||
| Acrylic acid | 79-10-7 | Propene acid, Acroleic acid |
| BIS-GMA | 1565-94-2 | Bisphenol A-glycidyl methacrylate |
| n-Butyl acrylate | 141-32-2 | n-Butyl acrylate, Butyl ester of acrylic acid, Butyl 2-propenoate |
| Ethyl acrylate | 140-88-5 | Acrylic acid ethyl ester |
| Ethyl cyanoacrylate | 7085-85-0 | Ethyl-2-cyanoacrylate, Krazy Glue, Super Glue |
| Ethyl methacrylate | 97-63-2 | |
| 2-Hydroxyethyl methacrylate | 808-77-9 | HEMA |
| 2-Hydroxypropyl acrylate | 999-61-1 | HPA |
| Methyl acrylate | 96-33-3 | Acrylic acid methyl ester |
| Methyl 2-cyanoacrylate | 137-05-3 | Adhere; Coapt; alpha-Cyanoacrylate acid methyl ester |
| Methyl methacrylate | 80-62-6 | Methacrylic acid methyl ester |
| Many other acrylates and methacrylates are known sensitizers, including: Tripropylene glycol diacrylate; tert-Butyl Acrylate; Bisphenol A diglycidylether diacrylate; 1,6-Hexanediol diacrylate; 2-Ethylhexyl acrylate; 1,4-Butanediol dimethacrylate; Ethyleneglycol dimethacrylate; Diethylene glycol dimethacrylate; Glycidyl methacrylate; 2-Hydroxypropyl methacrylate; Urethane dimethacrylate; Tetraethylene glycol dimethacrylate; Triethylene glycol dimethacrylate; Trimethylolpropane trimethacrylate; Pentaerythritol triacrylate; 2-Hydroxyethyl acrylate; Trimethylopropane triacrylate | ||
| Aldehydes | ||
| Acetaldehyde | 75-07-0 | |
| Cinnamic aldehyde | 104-55-2 | Cinnamal; cinnamaldehyde; 3-Phenyl-2-propenal; Phenylacrolein |
| Formaldehyde | 50-00-0 | Formalin |
| Glutaraldehyde | 111-30-8 | Cidex; Glutaric dialdehyde; 1,5-Pentanedial |
| Glyoxal | 107-22-2 | Biformal; Diformal; Ethandial; Ethanedial; Glyoxylaldehyde; Oxal; |
| Amines | ||
| Cyclohexylamine | 108-91-8 | |
| Diethylenetriamine | 111-40-0 | DETA |
| N,N-Dimethyl-1,3-propanediamine | 109-55-7 | DMAPA |
| Ethylenediamine | 107-15-3 | |
| Hexamethylene tetramine | 100-97-0 | Methenamine |
| N-(2-Hydroxyethyl)ethylenediamine | 111-41-1 | Aminoethylethanolamine |
| Isophorone diamine | 2855-13-2 | IPD |
| Piperazine dihydrochloride | 142-64-3 | Piperazine Hydrochloride; Diethylenediamine dihydrochloride |
| Triethanolamine | 102-71-6 | Triethylolamine, trolamine, TEA, trihydroxytriethylamine |
| Triethylene tetramine | 112-24-3 | TETA |
| Anhydrides | ||
| Maleic anhydride | 108-31-6 | |
| Methyltetrahydrophthalic anhydride | 26590-20-5 | |
| Phthalic anhydride | 85-44-9 | |
| Aromatic Amines | ||
| 2-Aminophenol | 95-55-6 | o-Aminophenol |
| 4-Aminophenol | 123-30-8 | p-Aminophenol |
| 4-Aminodiphenylamine | 101-54-2 | |
| 2,4-Diaminotoluene | 95-80-7 | Toluene-2,4-diamine |
| 3,3'-Dichlorobenzidine | 91-94-1 | Dichlorobenzidine base |
| 4-Dimethylaminoazobenzene | 60-11-7 | |
| Diphenylamine | 122-39-4 | |
| 4,4'-Methylenedianiline | 101-77-9 | MDA; 4,4'-Diaminodiphenylmethane; 4,4' Methylene bis (2-chloraniline); Diaminodiphenylmethane; DDM; |
| p-Phenylene diamine | 106-50-3 | |
| p-Toluylenediamine | 95-70-5 | |
| m-Xylene alpha,alpha'-diamine | 1477-55-0 | 1,3-Benzenedimethanamine |
| Aromatic Nitros | ||
| Dinitrotoluene, all isomers | 25321-14-6 | |
| 2-Nitro-4-phenylenediamine | 5307-14-2 | o-Nitro-4-phenylenediamine |
| Picric acid | 88-89-1 | Phenol trinitrate; 2,4,6-Trinitrophenol |
| Tetryl | 479-45-8 | 2,3,6-Trinitrophenylmethylnitramine |
| Beauty Culture | ||
| Ammonium persulfate | 7727-54-0 | Ammonium peroxydisulfate; ammonium persulphate |
| Ammonium thioglycolate | 5421-46-5 | Ammonium mercaptoacetate |
| Glyceryl monothioglycolate | 30618-84-9 | GMTG |
| Carbamates | ||
| Carbofuran | 1563-66-2 | Furadan |
| Carbaryl | 63-25-2 | Sevin |
| Methomyl | 16752-77-5 | Lannate |
| Epoxy Resins | ||
| Bisphenol A | 80-05-7 | 4,4'-Isopropylidenediphenol |
| Bisphenol A diglycidyl ether | 1675-54-3 | |
| Epichlorohydrin | 106-89-8 | 1-Chloro-2,3-epoxypropane |
| Glycidol | 556-52-5 | 2,3-Epoxy-1-propanol |
| Triglycidyl isocyanurate | 2451-62-9 | TGIC |
| Formaldehyde Resins | ||
| p-tert-Butylphenol formaldehyde resin | PTBP formaldehyde resin | |
| Melamine formaldehyde | 13236-84-5 | Kaurit M70 |
| Phenol-formaldehyde resin | 9003-35-4 | P-F-R-2; Resol; Phenol formaldehyde; Novolac |
| Toluenesulfonamide formaldehyde resin | 25035-76-1 | Santolite MHP; Santolite MS |
| Urea formaldehyde | 9011-05-6 | Kaurit S |
| Fungicides | ||
| Benomyl | 17804-35-2 | |
| Chlorothalonil | 1897-45-6 | Tetrachloroisophthalonitrile |
| Captafol | 2425-06-1 | Difolatan |
| Maneb | 12427-38-2 | |
| Ferbam | 14484-64-1 | |
| Folpet | 133-07-3 | |
| Zineb | 12122-67-7 | |
| Thiram | 137-26-8 | Tetramethylthiuram disulfide |
| Captan | 133-06-2 | |
| Mancozeb | 8018-01-7 | |
| Triforine | 26644-46-2 | |
| Bupirimate | 41483-43-6 | |
| Fluazinam | 79622-59-6 | |
| Metam-Sodium | 137-42-8 | |
| Pentachloronitrobenzene | 82-68-8 | |
| Plondrel | 5131-24-8 | |
| Ziram | 137-30-4 | |
| Organophosphates | ||
| Dichlorvos | 62-73-7 | DDVP |
| Malathion | 121-75-5 | |
| Methidathion | 950-37-8 | Supracide |
| Methyl parathion | 298-00-0 | |
| Naled | 300-76-5 | Dibrom |
| Omethoate | 1113-02-6 | |
| Phosdrin | 7786-34-7 | Mevinphos |
| Trichlorfon | 52-68-6 | |
| Herbicides | ||
| Alachlor | 15972-60-8 | |
| Barban | 101-27-9 | |
| Dinocap | 39300-45-3 | |
| Phenmedipham | 13684-63-4 | |
| Glycidyl Ethers | ||
| Allyl glycidyl ether | 106-92-3 | AGE |
| n-Butyl glycidyl ether | 2426-08-6 | BGE |
| Cresyl glycidyl ether | 26447-14-3 | |
| Isopropyl glycidyl ether | 4016-14-2 | IGE |
| alpha-Naphtyl glycidyl ether | 2461-42-9 | |
| Phenyl glycidyl ether | 122-60-1 | PGE |
| Isocyanates | ||
| Hexamethylene diisocyanate | 822-06-0 | HDI |
| Isophorone diisocyanate | 4098-71-9 | IPDI |
| Methylene bisphenyl isocyanate | 101-68-8 | MDI; Diphenylmethane diisocyanate |
| Naphthalene diisocyanate | 25551-28-4 | NDI |
| Toluene diisocyanate | 584-84-9 | TDI; 2,4-Toluene diisocyanate |
| Metals | ||
| Arsenic and compounds | varies | |
| Chromium and compounds | varies | Dermal and respiratory sensitization to chromate in a cement floorer |
| Cobalt | 7440-48-4 | Cobalt metal dust, Cobalt metal fume |
| Gold and compounds | 7440-57-5 | |
| Mercury | 7439-97-6 | Increase in occupational skin diseases of dental personnel |
| Nickel and compounds | varies | Nickel as an occupational allergen. A survey of 368 nickel-sensitive subjects |
| Palladium | 7440-05-3 | |
| Platinum, soluble salts | 7440-06-4 | |
| Tin, inorganic compounds | 7440-31-5 | |
| Tungsten carbide | 12070-12-1 | |
| Solvents | ||
| Benzyl alcohol | 100-51-6 | |
| Cyclohexanone | 108-94-1 | |
| o-Dichlorobenzene | 95-50-1 | 1,2-Dichlorobenzene |
| 1,3-Dichloropropene | 542-75-6 | |
| Dioxane | 123-91-1 | Diethylene dioxide |
| Hexylene glycol | 107-41-5 | |
| d-Limonene | 138-86-3 | |
| Propylene glycol | 57-55-6 | |
| Turpentine | 8006-64-2 | |
| Phenols | ||
| Catechol | 120-80-9 | Pyrocatechol |
| Hydroquinone | 123-31-9 | Dihydroxybenzene |
| 2-Methylol phenol | 623-05-2 | |
| Pyrogallol | 87-66-1 | |
| Resorcinol | 108-46-3 | |
| Photography | ||
| p-Amino-N,N-diethylaniline sulfate | 6065-27-6 | |
| CD-1 | 2198-58-5 | |
| CD-2 | 2051-79-8 | |
| CD-3 | 25646-71-3 | |
| CD-4 | 25646-77-9 | |
| p-Methylaminophenol sulfate | 55-55-0 | Metol |
| Phenidone | 92-43-3 | 1-Phenyl-3-pyrazolidone |
| Phthalate Esters | ||
| Dibutyl phthalate | 84-74-2 | DBP; Dibutyl 1,2-benzene-dicarboxylate; Di-n-butyl phthalate |
| Diethyl phthalate | 84-66-2 | DEP, Diethyl ester of phthalic acid, Ethyl phthalate |
| Dimethylphthalate | 131-11-3 | Dimethyl ester of 1,2-benzenedicarboxylic acid; DMP |
| Preservatives/Disinfectants | ||
| Benzalkonium chloride | 8001-54-5 | Zephiran |
| 1,2-Benzisothiazolin-3-one | 2634-33-5 | BIT |
| Bioban CS-1246 | 7747-35-5 | |
| Bioban P-1487 | 37304-88-4 | |
| Bromonitrodioxane | 30007-47-7 | |
| Bronopol | 52-51-7 | |
| Butylated hydroxyanisole | 25013-16-5 | BHA |
| Chloramine T | 127-65-1 | |
| Chloroacetamide | 79-07-2 | |
| 4-Chloro-3-xylenol | 88-04-0 | PCMX |
| Dazomet | 533-74-4 | |
| Diazolidinyl urea | 78491-02-8 | |
| Dimethylol urea | 140-95-4 | |
| DMDM hydantoin | 6440-58-0 | |
| Grotan BK | 4719-04-4 | |
| Imidazolidinyl urea | 39236-46-9 | |
| Lauryl dimethyl benzyl ammonium chloride | 139-07-1 | Benzenemethanaminium,N-dodecyl-N,N-dimethyl-,chloride |
| Quaternium 15 | 51229-78-8 | Dowicil 75, 100, 200 (chemically similar); Dowicil 200; |
| Thimerosal | 54-64-8 | Merthiolate |
| Rubber Chemicals | ||
| Azodicarbonamide | 123-77-3 | 1,1'-Azobisformamide |
| Black rubber mix | N,N'-diphenyl-p-phenylenediamine (DPPD); N-Isopropyl-N-phenyl-4-phenylenediamine (IPPD); N-phenyl-N'-cyclohexyl-p-phenylenediamine (CPPD); | |
| Carba Mix | 1,3-Diphenylguanidine (DPG), Zinc dibutyldithiocarbamate (ZBC); Zinc diethyldithiocarbamate (ZDEC) | |
| Disulfiram | 97-77-8 | Antabuse, Tetraethylthiuram disulfide |
| Ethylene thiourea | 96-45-7 | ETU |
| Mercaptobenzothiazole | 149-30-4 | MBT |
| Mercapto mix | 2,2'-Benzothiazyl disulfide (MBTS) 4-Morpholinyl-2-benzothiazyl disulfide (MMBT) N-cyclohexyl-2-benzothiazole sulfenamide (CBS) |
|
| Santonox | 96-69-5 | 4,4`-Thiobis-(6-tert-butyl-m-cresol) |
| Thiuram mix | Dipentamethylenethiuram disulfide: (PTD); Tetraethylthiuram disulfide (TEDT); Tetramethylthiuram disulfide (TMTD); Tetramethylthiuram monosulfide (TMTM) | |
| Miscellaneous | ||
| Acrylamide | 79-06-1 | |
| Acrylonitrile | 107-13-1 | Vinyl cyanide |
| Allyl propyl disulfide | 2179-59-1 | |
| Benzoyl peroxide | 94-36-0 | Benzoperoxide, Dibenzoyl peroxide |
| Calcium cyanamide | 156-62-7 | |
| Caprolactam | 105-60-2 | |
| alpha-Chloroacetophenone | 532-27-4 | Mace(R), "CN" |
| o-Chlorobenzylidene malonitrile | 2698-41-1 | "CS" |
| Cocamide DEA | 68603-42-9 | |
| Cocamidopropyl betaine | 86438-79-1 | |
| Cyanamide | 420-04-2 | |
| Cyclohexanone peroxide | 78-18-2 | |
| 1,2-Dibromo-2,4-dicyanobutane | 35691-65-7 | |
| Diglycolamine | 929-06-6 | |
| 1-Dodecanethiol | 112-55-0 | Dodecylmercaptan |
| Drugs | ||
| Ethylene oxide | 75-21-8 | |
| Ethylenimine | 151-56-4 | |
| Fenvalerate | 51630-58-1 | |
| Glycidyl trimethyl ammonium chloride | 3033-77-0 | EPTMAC |
| Hydrazine | 302-01-2 | |
| Hydroxylamine | 7803-49-8 | |
| Methyl isocyanate | 624-83-9 | |
| Ninhydrin | 485-47-2 | |
| Nitroglycerin | 55-63-0 | |
| Phenylhydrazine | 100-63-0 | |
| Portland cement | 65997-15-1 | |
| Pyrethrum | 8003-34-7 | |
| Pyridine | 110-86-1 | |
| Rosin core solder | 8050-09-7 | Rosin flux pyrolysis products |
| Sodium metabisulfite | 7681-57-4 | |
| Styrene | 100-42-5 | |
| Textile dyes | ||
| Triphenyl phosphate | 115-86-6 | |
| Vinyl cyclohexene dioxide | 106-87-6 | |
For more details and references, see Haz-Map on the the NLM web site.
Revised May 30, 2018
