Haz-Map
includes all chemicals in the American Conference of Governmental Industrial Hygienists (ACGIH)
database. ACGIH fields in Haz-Map are Cancer Designation, Skin Designation,
Biological Exposure Index (BEI), TLV, STEL, and Ceiling. The last three are
recommended occupational exposure levels (workplace air levels not to be
exceeded). ACGIH profiles are updated regularly and include summaries of
occupational epidemiology and animal toxicology for each substance covered.
The “2010 Supplement to the 7th Edition” has 21 profiles of
newly adopted or updated substances (15 for TLVs and 6 for BEIs). The 2011 and
2012 supplements were purchased and reviewed: 9 for TLVs and 1 for BEIs (2011
profiles) and 8 for TLVs and 2 for BEIs (2012 profiles). Review of the 2013
TLVs and BEIs and 2013 Supplement to the 7th Edition was completed
and will be published later this year.
Haz-Map
includes all chemicals in the NIOSH Pocket Guide. There are 322 chemicals in
Haz-Map with IDLHs (warning air levels for Immediately Dangerous for Life and
Health). The NIOSH Pocket Guide is based on research from over 40 years ago,
and the disease information does not reflect the current state of scientific knowledge. There are no
references in the Pocket Guide. The lists of symptoms and target organs have
not changed when comparing the 1997 and 2007 editions.
The introductions in those two editions mention some revisions to parts
of the Pocket Guide but not to the symptoms or target organs. The Pocket Guide
does not distinguish between symptoms of acute or chronic diseases; it does
not distinguish between adverse effects caused by animal experiments,
poisoning by ingestion, or occupational exposure.
ChemIDplus
contains over 380,000 records and over 295,000 chemical structures with links
to other chemical databases on the web. Hazardous
Substances Data Bank (HSDB) contains over 5,000 profiles on toxic chemicals,
updated by specialists at the US National Library of Medicine and peer
reviewed by the Scientific Review Panel. Haz-Map includes all HSDB chemicals
that are important in terms of occupational exposure.
"The
ATSDR toxicological profile succinctly characterizes the toxicologic and
adverse health effects information for the hazardous substance described here.
Each peer-reviewed profile identifies and reviews the key literature that
describes a hazardous substance's toxicologic properties." There are
about 300 chemical toxicological profiles. About 30 "Case Studies"
profiles have been published.
EPA
CAMEO (6000+)
CAMEO
Chemicals is a database of over 6,000 hazardous materials commonly
transported, used, or stored in the United States; it has information about
fire and explosive hazards and health effects developed by EPA and NOAA to
assist emergency responders. Approximately 2700 Haz-Map chemicals include the
"Reactive Groups" categories shown in CAMEO. These "Reactive
Groups" in CAMEO help to classify chemicals into one of 12 main
categories and one of 200+ subcategories in Haz-Map. A list of subcategories,
as of March 2011, is here.
EXTOXNET
is a cooperative effort of University of California-Davis, Oregon State
University, Michigan State University, Cornell University, and the University
of Idaho. Primary files are maintained and archived at Oregon State
University. The 183 pesticides covered by EXTOXNET are included in Haz-Map.
There
are about 2500 chemicals in Haz-Map with ERG 2012 information: links to the
specific Guides and designations of "Explosive Polymerization,"
"Dangerous When Wet," and "TIH" (Toxic Inhalation Hazard).
The Emergency Response Guidebook was developed jointly by the US Department of
Transportation, Transport Canada, and the Secretariat of Communications and
Transportation of Mexico, and Centro de Informacion Quimica para Emergencias
of Argentina as an aid for firefighters, police, and other
emergency responders to quickly identify hazardous materials and to protect
themselves and the general public at the time of chemical spills or releases.
For each hazardous chemical, the first responder is referred to one of 62
Guides, e.g., Guide 125 (Gases - Corrosive) or Guide 127 (Flammable Liquids).
ERG 2012 is used to help classify chemicals in Haz-Map. It is also used to
help define "Pneumonitis, toxic."
A
joint project of the International Programme on Chemical Safety (IPCS) and the
Canadian Centre for Occupational Safety (CCOHS), this Internet portal provides
access to profiles for thousands of chemicals. Important databases accessible
through INCHEM include International Chemical Safety Cards (ICSC),
International Agency for Research on Cancer (IARC) Monographs, Joint Expert
Committee on Food Additives (JECFA) Monographs, Joint Meeting on Pesticide
Residues (JMPR) Monographs, and Screening Information Data Set (SIDS) for High
Production Volume Chemicals.
These
are the REDs (Reregistration Eligibility Decisions) for dozens of individual
pesticide active ingredients. RED documents contain the results of EPA's
regulatory reviews of pesticides initially registered before November 1, 1984.
RTECS
is data from animal experiments extracted from the open scientific literature
and includes primary irritation, mutagenic effects, reproductive effects,
tumorigenic effects, acute toxicity, and other multiple dose toxicity. RTECS
provides values for LD50 and LC50 as well as route of administration and species studied.
Chemical hazard information for EH&S
Professionals, ExPub has millions of documents from over 100 sources.
Document sites include: EPA OHM/TADS (Oil
and Hazardous Materials Technical Assistance Data System, EPA
ChAMP (Chemical Assessment and Management Program), REPROTOX, RTECS (Registry of Toxic Effects of
Chemical Substances), FDA (US Food
and Drug Administration), EFSA
(European Food Safety Authority), and OECD SIDS
(Organization for Economic Co-operation and Development Screening
Information Data Set). Subscription is required for ExPub.
SEM
(15,000+)
The
SEM (Site Exposure Matrix) database contains over 15,000
chemicals/trade names based on records of chemicals used at U.S. federal
facilities for nuclear weapons research and development during the Cold War.
Many of these chemical are rarely used, and information is scarce. Whenever
possible, these chemicals are compared to more well-known chemicals with
similar structures. The SEM database also includes many common chemicals
of biological origin that were not originally in Haz-Map. It was decided to
add rather than ignore these biological agents (monosaccharides, amino acids,
proteins, vitamins, etc.) because they demonstrate that all chemicals are
toxic at sufficient dose, and their structures can be compared to other
chemicals already in the database. Haz-Map does not include drugs unless they
are involved in important occupational exposures. Generally, it does not
include alloys or commercial mixtures.
For other books and databases used
to make Haz-Map, see the Bibliography page.