m-Nitroaniline

Synonyms

1-Amino-3-nitrobenzene; 3-Aminonitrobenzene; 3-Nitroaniline; 3-Nitrobenzenamine; 3-Nitrophenylamine; Amarthol Fast Orange R Base; Aniline, m-nitro-; Azobase MNA; Benzenamine, 3-nitro-; C.I. 37030; C.I. Azoic Diazo Component 7; CI 37030; CI Azoic Diazo Component 7; Daito Orange Base R; Devol Orange R; Diazo Fast Orange R; Fast Orange Base R; Fast Orange M Base; Fast Orange MM Base; Fast Orange R Base; Fast Orange R Salt; Hiltonil Fast Orange R Base; MNA; Naphtoelan Orange R Base; Nitranilin; Orange Base Irga I; m-Aminonitrobenzene; m-Nitraniline; m-Nitroaminobenzene; m-Nitroaniline; m-Nitrophenylamine; [ChemIDplus] UN1661

Category

Nitroanilines

Description

Yellow needle-like crystals; burning, sweet odor; [CHEMINFO]

Sources/Uses

Used as a "color test for pine wood" and in the synthesis of organic chemicals; [HSDB]

Comments

m-Nitroaniline is in the ACGIH table of "Industrial Chemicals for Which Methemoglobin Formation is the Principal Cause of Toxicity." It emits toxic fumes of nitrogen oxides when heated. Methemoglobinemia has been reported after acute exposure and liver injury after chronic exposure. m-Nitroaniline is toxic after ingestion, inhalation, and skin exposure. [HSDB] Can induce methemoglobinemia; [ICSC]

Biomedical References

Methemoglobin in blood = 1.5% of hemoglobin during or at end of shift. [ACGIH]

9.56E-05 mm Hg

Explanatory Notes

mp = 114 deg C; bp = 306 deg C (decomposes); Flash point = 199 deg C; VP from HSDB;

MetHgb is primary toxic effect

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Methemoglobinemia, acute