Isopropylidene glycerol
Agent Name
Isopropylidene glycerol
Alternative Name
2,2-Dimethyl-1,3-dioxolane-4-methanol
CAS Number
100-79-8
Formula
C6-H12-O3
Major Category
Solvents
Synonyms
2,2-Dimethyl-1,3-dioxolane-4-methanol; 1,2-Isopropylideneglycerin; 1,2-Isopropylideneglycerol; 1,2-O,O-Isopropylideneglycerin; 1,2-O-Isopropylideneglycerol; 2,2-Dimethyl-1,3-dioxolan-4-yl methanol; 2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxacyclopentane; 2,2-Dimethyl-4-hydroxymethyldioxolane; 2,2-Dimethyl-4-oxymethyl-1,3-dioxolane; 2,2-Dimethyl-5-hydroxymethyl-1,3-dioxolane; 2,3-(Isopropylidenedioxy)propanol; 2,3-Isopropylideneglycerol; 4-Hydroxymethyl-2,2-dimethyl-1,3-dioxolane; Acetone glycerol; Acetone monoglycerol ketal; Acetone, cyclic (hydroxymethyl)ethylene acetal; Dioxolan; GIE; Glycerinisopropylidene ether; Glycerol acetonide (VAN); Glycerol dimethylketal; Glycerol, 1,2-O-isopropylidene; Glycerolacetone; Solketal; alpha,beta-Isopropylideneglycerol; 1,3-Dioxolane-4-methanol, 2,2-dimethyl-; [ChemIDplus]
Category
Other Solvents
Description
Nearly odorless liquid; [Merck Index] Colorless oily liquid; Odorless; [ICSC]
Sources/Uses
Used as solvent, plasticizer, and pharmaceutical aid (solubilizing and suspending agent); [Merck Index]
Comments
An eye irritant; Causes change in heart rate and blood pressure in intravenous lethal-dose studies of rats and rabbits; [RTECS] An eye irritant; [ICSC] May cause irritation; [Alfa Aesar MSDS] See "1,3-Dioxolane."
Biomedical References
Exposure Assessment
Vapor Pressure
107 mm Hg
Explanatory Notes
VP from ChemIDplus;
NFPA
may ignite at ambient temp
Adverse Effects
Neurotoxin
Acute solvent syndrome
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: