Toluene-2,5-diamine sulfate

Synonyms

2,5-Diaminotoluene sulfate; 1,4-Benzenediamine, 2-methyl-, sulfate; 2-Methyl-1,4-benzenediamine sulfate; 2,5-Diaminotoluene sulphate; 2-Methyl-p-phenylenediamine sulfate; 2-Methyl-p-phenylenediamine sulphate; C.I. 76043 (VAN); CI 76043; Toluene-2,5-diamine sulphate; Toluene-2,5-diamine, sulfate; Toluylene-2,5-diamine sulfate; Toluylene-2,5-diamine sulphate; p-Diaminotoluene sulfate; p-Toluenediamine sulfate; p-Toluenediamine sulphate; p-Toluylenediamine sulfate; p-Toluylenediamine sulphate; p-Tolylenediamine sulfate; p-Tolylenediamine sulphate; [ChemIDplus] UN2811

Category

Amines, Aromatic

Description

Grey to white solid; [ICSC] Light brown powder; [Sigma-Aldrich MSDS]

Sources/Uses

Used in hair dyes; [EC - SCCS]

Comments

A mild skin and eye irritant; May cause skin sensitization; Can be absorbed through skin; [ICSC] A potent skin sensitizer, with positive patch test results observed in hairdressers with dermatitis; In 14-day feeding studies of rats, causes increased AST, CPK, LDH, and ALT at 60 mg/kg/day; [EC - SCCS] May cause irritation; Toxic by ingestion; [Sigma-Aldrich MSDS] See "2,5-Diaminotoluene."

Biomedical References

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Toxic solid, organic, n.o.s."

Yes

MetHgb is secondary toxic effect

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic

Processes

Industrial Processes with risk of exposure:

• Dressing Hair