Toluene-2,5-diamine sulfate

Agent Name
Toluene-2,5-diamine sulfate
Alternative Name
2,5-Diaminotoluene sulfate
CAS Number
615-50-9
Formula
C7-H10-N2.H2-O4-S
Major Category
Nitrogen Compounds
Toluene-2,5-diamine sulfate formula graphical representation
Synonyms
2,5-Diaminotoluene sulfate; 1,4-Benzenediamine, 2-methyl-, sulfate; 2-Methyl-1,4-benzenediamine sulfate; 2,5-Diaminotoluene sulphate; 2-Methyl-p-phenylenediamine sulfate; 2-Methyl-p-phenylenediamine sulphate; C.I. 76043 (VAN); CI 76043; Toluene-2,5-diamine sulphate; Toluene-2,5-diamine, sulfate; Toluylene-2,5-diamine sulfate; Toluylene-2,5-diamine sulphate; p-Diaminotoluene sulfate; p-Toluenediamine sulfate; p-Toluenediamine sulphate; p-Toluylenediamine sulfate; p-Toluylenediamine sulphate; p-Tolylenediamine sulfate; p-Tolylenediamine sulphate; [ChemIDplus] UN2811
Category
Amines, Aromatic
Description
Grey to white solid; [ICSC] Light brown powder; [Sigma-Aldrich MSDS]
Sources/Uses
Used in hair dyes; [EC - SCCS]
Comments
A mild skin and eye irritant; May cause skin sensitization; Can be absorbed through skin; [ICSC] A potent skin sensitizer, with positive patch test results observed in hairdressers with dermatitis; In 14-day feeding studies of rats, causes increased AST, CPK, LDH, and ALT at 60 mg/kg/day; [EC - SCCS] May cause irritation; Toxic by ingestion; [Sigma-Aldrich MSDS] See "2,5-Diaminotoluene."
Biomedical References

Exposure Assessment

Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Toxic solid, organic, n.o.s."

Adverse Effects

Skin Sensitizer
Yes
Methemoglobinemia
MetHgb is secondary toxic effect
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: