Mancozeb

Synonyms

Dithane, Dithane-Ultra, Fore, Green-Daisen M, Karamate, Mancofol, Mancozin, Manzate 200, Manzeb, Manzin Nemispor, Nemispot, Policar, Riozeb, Zimaneb; [EXTOXNET]

Category

Dithiocarbamates (Pesticide)

Description

Available as gray-yellow powder with a musty odor containing 80% product and 20% other surfactants and diluents; [AIHA]

Sources/Uses

A wide-spectrum fungicide used on seeds, fruits, vegetables, nuts, and field crops; [EXTOXNET] A protective eradicant and nonsystemic fungicide; [AIHA]

Comments

Classified as "practically nontoxic," mancozeb can cause occupational allergic contact dermatitis. [EXTOXNET] The EBCDCs (ethylenebisdithiocarbamates) can cause irritant and allergic contact dermatitis. EBDCs include ferbam, vapam, maneb, mancozeb, zineb, thiram, and ziram. They are also used as rubber accelerators. Ethylene thiourea (ETU), which may contaminate EBCDCs, is carcinogenic and teratogenic in animal experiments. [LaDou, p. 610] ETU is the major metabolite of EBDCs. [Krieger, p. 1690] In high-dose reproductive studies of animals, mancozeb causes testicular damage, fetal losses, and birth defects (hydrocephalus). [Frazier, p. 230-1] Potential for dermal sensitization; [AIHA: WEELs] Decomposes on heating and on contact with acids and moisture--chemicals produced include manganese oxide. [ICSC] See "Ethylene thiourea." See "Manganese" and linked occupational diseases. The TLV for manganese is for elemental and inorganic compounds. Mancozeb is an organic compound containing manganese.

Reference Link #1

Biomedical References

Reference Link #2

1 mg/m3

Yes

Parkinsonism

Yes

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic
• Manganese, chronic toxic effect

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)