4-Ethyltoluene

Synonyms

1-Ethyl-4-methylbenzene; 1-Methyl-4-ethylbenzene; 4-Methylethylbenzene; p-Ethylmethylbenzene; p-Ethyltoluene; p-Methylethylbenzene; Benzene, 1-ethyl-4-methyl-; Toluene, p-ethyl-; [ChemIDplus] UN3295

Category

Aromatic Solvents

Description

Liquid; [EPA ChAMP: Hazard Characterization: p-Ethyltoluene - 2009] Colorless liquid; [Alfa Aesar MSDS]

Comments

A skin and eye irritant in rabbits; Effects on mortality and clinical chemistry (increased ALT, alkaline phosphatase, and albumin), observed in 13-week oral studies of rats at 300 mg/kg/day; Male reproductive system effects (testicular atrophy and decreased spermatogenesis observed at 900 mg/kg; A 13-week inhalation study of rats demonstrated significant changes in liver and gonad weights at 4,800 mg/m3/day; [EPA ChAMP: Hazard Characterization: p-Ethyltoluene - 2009] May cause irritation; Harmful by ingestion (may cause lung damage by aspiration); [Alfa Aesar MSDS] See "1-Ethyl-2-methylbenzene."

Biomedical References

3 mm Hg

LC50 (rat) > 19,000 mg/m3/6hr

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Hydrocarbons, liquid, n.o.s." VP from ChemIDplus;

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Solvents, acute toxic effect