p-Nitroanisole
Agent Name
p-Nitroanisole
CAS Number
100-17-4
Formula
C7-H7-N-O3
Major Category
Nitrogen Compounds
Synonyms
1-Methoxy-4-nitrobenzene; 4-Methoxynitrobenzene; Nitroanisole; p-Methoxynitrobenzene; p-Nitroanisol; 4-Nitroanisole; Anisole, p-nitro-; Benzene, 1-methoxy-4-nitro-; [ChemIDplus] UN2730; UN3458
Category
Other Aromatics (Nitrogen)
Description
Solid; [Merck Index] Beige crystalline solid; [Sigma-Aldrich MSDS]
Sources/Uses
Used as a dye intermediate and for organic synthesis; [ChemIDplus]
Comments
Causes fatty liver degeneration in oral lethal-dose studies of mice; [RTECS] A strong oxidizing agent; May cause skin, eye, and mucous membrane irritation; [CAMEO] May cause irritation; May induce methemoglobinemia; [Sigma-Aldrich MSDS] See "o-Nitroanisole."
Biomedical References
Exposure Assessment
Vapor Pressure
0.019 mm Hg
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Nitroanisoles."
Adverse Effects
Methemoglobinemia
MetHgb is secondary toxic effect
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Possible (2b)
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.